Anemia in patients with spondyloarthritis


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Abstract

Objective: to evaluate specifics of anemic syndrome and to determine associations anemia with clinical and laboratory values of the disease. Material and methods. Hemogram, iron metabolism, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were evaluated in 110 patients with spondyloarthritis (SpA). Associations between hemoglobin level and BASDAI, ASDAS-CRP, BASFI, laboratory values of systemic inflammatory activity are determined. Results. Anemia was found in 39.1% of patients with SpA, 88.4% of them had mild anemia. Anemia of chronic disease (ACD) and iron deficiency anemia (IDA) was found in 70.3% patients. The inverse relationship between the concentration of hemoglobin and ESR, the level of CRP are revealed. The decrease in hemoglobin level did not depend on the increase of BASDAI and BASFI scores. Conclusion. Anemia is a relevant problem for the patients with SpA. The association between hemoglobin level, ESR, and the level of CRP is a clinical reflection of the pathophysiological mechanisms of the relationship between inflammation and anemia.

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About the authors

Karina N. Tsaturova

Federal State Budgetary Educational Institution of Hidher Education V.I. Razumovsky Saratov state medical university of the Ministry of Healthcare of Russia

Email: k.tsaturova@yandex.ru
attending physician of the chair of hospital therapy of general medicine Department

Kseniya D. Dorogoykina

Federal State Budgetary Educational Institution of Hidher Education V.I. Razumovsky Saratov state medical university of the Ministry of Healthcare of Russia

Email: axxxinya@mail.ru
PhD candidate of hospital therapy chair of general medicine Department

Violetta I. Machina

Federal State Budgetary Educational Institution of Hidher Education V.I. Razumovsky Saratov state medical university of the Ministry of Healthcare of Russia

Email: violettamakhina@mail.ru
PhD candidate of hospital therapy chair of general medicine Department

Andrey P. Rebrov

Federal State Budgetary Educational Institution of Higher Professional Education V.I. Razumovskii Saratov state medical university of the Ministry of Healthcare of the Russian Federation

Email: andreyrebrov@yandex.ru
professor, MD, head of the Department of hospital therapy of general medicine faculty

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