The way of preventing acute respiratory infections and COVID-19 in healthcare workers


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Abstract

The aim of the study: to assess the prophylactic efficacy of the Polyoxidonium in healthcare workers working with patients with COVID-19. Material and methods. The study included 913 medical staff working in the «red zones» of hospitals. The main group included 577 people who received Polyoxidonium tablets 12 mg (under the tongue) once a day for 30 days. Control group included 366 people who did not receive any prophylactic drugs. The number of ARI and COVID-19 diseases was assessed for 2 months (within 1 month of taking the drug and 1 month after taking the drug) by interviewing medical personnel using specially prepared questionnaires. To assess the duration of the effect of taking the drug, the second wave of the survey was conducted, in which the number of cases of ARI and COVID-19 was assessed during the period of taking the drug and within 3 months after the end of taking the drug. The second wave of the survey involved 350 health workers from those who took part in the first wave of the survey. Of these study 115 participants, 247 people took Polyoxidonium, 103 people did not take any medications. Results. With the use of Polyoxidonium, a significant decrease in the number of cases of ARI and COVID-19 was recorded compared to the control group. According to the data of the first wave of the survey, 0,7% of the participants in the main group fell ill with ARI, and 0,3% of COVID-19. In the control group, 12,2% fell ill with ARI, 5,1% - COVID-19. According to the second wave of the survey, 13,1% of participants in the main group fell ill with ARI, and 2,4% of COVID-19. In the control group, 57,3% fell ill with ARI and 26,2% with cOvID-19. In the main group, none of the participants contracted pneumonia, while in the control group, pneumonia was noted in 42,5% of ARI cases. In addition, the use of Polyoxidonium significantly reduces the number of cases of ARI and COVID-19 in medical workers suffering from chronic diseases (0,3% of participants had ARI and COVID-19 in the main group, in the control group 28,1% and 9,9% of participants had ARI and COVID-19 respectively). 86,9% of the surveyed medical workers considered the prevention with the help of Polyoxidonium effective and 88,2% of the respondents would like to continue it. Conclusion. The use of Polyoxidonium in medical workers has led to a significant decrease in cases of ARI and COVID-19, pneumonia. The use of Polyoxidonium probably contributes to an easier course of the disease in case of its onset.

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About the authors

Vera P. Vavilova

Kemerovo State Medical University of the Ministry of Healthcare of Russia

Email: vavilovavр@mail.ru
MD, professor of the Department of outpatient pediatrics, propedeutics of childhood diseases and postgraduate training 650059, Kemerovo, 22А Voroshilova Str

Alexander M. Vavilov

Kemerovo State Medical University of the Ministry of Healthcare of Russia

Email: vavilovalexandr@mail.ru
MD, professor of the Department of propedeutics of internal diseases 650059, Kemerovo, 22А Voroshilova Str

Nina K. Perevoshchikova

Kemerovo State Medical University of the Ministry of Healthcare of Russia

Email: nkp42@mail.ru
MD, professor, head of the Department of outpatient pediatrics, propedeutics of childhood diseases and postgraduate training 650059, Kemerovo, 22А Voroshilova Str

Sofia A. Tsarkova

Ural State Medical University of the Ministry of Healthcare of Russia

Email: tsarkova_ugma@bk.ru
MD, professor, head of the Department of Outpatient Pediatrics and Pediatrics of the Faculty of advanced training and professional retraining 620028, Ekaterinburg, 3 Repina Str

Irina I. Klimova

Novokuznetsk State Institute for Advanced Training of Physicians - branch of Russian Medical Academy of Continuing Professional Education of the Ministry of Healthcare of Russia

Email: iikl@mail.ru
MD, professor of the Department of otorhinolaryngology named after professor A.N. Zimin 654005, Novokuznetsk, 5 Stroiteley Avenue

Svetlana V. Kudasheva

Kuzbass Clinical Infectious Diseases Hospital

Email: gikb8glv@mail.ru
Chief physician 650036, Kemerovo, 43B Volgogradskaya Str

Igor V. Pachgin

Kuzbass Clinical Emergency Hospital named after M.A. Podgorbunsky

Email: kmr-obsmp@kuzdrav.ru
PhD, Chief physician 650000, Kemerovo, 22 Nikolaya Ostrovskogo Str

Ruslan A. Belous

Amur Regional Children's Clinical Hospital

Email: berual@rambler.ru
PhD, Chief physician 675005, Blagoveshchensk, 108 Oktyabrskaya Str

Vasili V. Malchikov

Novokuznetsk City Clinical Hospital No. 1

Email: mvv@1gkb-nk.ru
Chief physician 654057, Novokuznetsk, 28 Bardina Avenue

Mikhail S. Gordeev

Belovo City Hospital No. 1

Email: m.s.gordeev@mail.ru
Chief physician 652600, Belovo, 16 Chkalova Str

Olga L. Kozlova

Anzhero-Sudzhensk City Hospital

Email: as-cgb@mail.ru
Chief physician 652477, Anzhero-Sudzhensk, 3 Kubanskaya Str

Oksana F. Belousova

Anzhero-Sudzhensk City Hospital

Email: as-cgb@mail.ru
Deputy Chief physician for clinical work 652477, Anzhero-Sudzhensk, 3 Kubanskaya Str

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