Rare combination of ANCA-associated glomerulonephritis with systemic lupus erythematosus

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Abstract

Lupus nephritis is a classic immunocomplex glomerulonephritis. Kidney damage associated with antineutrophil cytoplasmic antibodies is a low-immune focal and segmental necrotizing/lunate glomerulonephritis that could be developed both separately and as part of systemic vasculitis. The aim of the research is to present and analyze an extremely rare clinical observation of female patient with systemic lupus erythematosus, identified antibodies to the cytoplasm of neutrophils and morphologically verified low-immune glomerulonephritis. The choice of treatment tactics in current clinical situation is substantiated.

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About the authors

Elena V. Voloshinova

V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia

Author for correspondence.
Email: voloshinovaelena@mail.ru
ORCID iD: 0000-0002-6883-0567

PhD in Medical Sciences, Associate Professor of the Department of Hospital Therapy

Russian Federation, Saratov

Elena V. Grigoryeva

V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia

Email: lek133@yandex.ru
ORCID iD: 0000-0001-6064-560X

PhD in Medical Sciences, Associate Professor of the Department of Hospital Therapy

Russian Federation, Saratov

Natalia M. Nikitina

V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia

Email: nikina02@yandex.ru
ORCID iD: 0000-0002-0313-1191

MD, Professor of the Department of Hospital Therapy

Russian Federation, Saratov

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