Peculiarities of metabolically healthy obesity among the population aged 45–69
- 作者: Berezenko I.L.1, Filippov E.V.1, Volchenkova M.V.1
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隶属关系:
- Academician I.P. Pavlov Ryazan State Medical University of the Ministry of Healthcare of Russia
- 期: 卷 11, 编号 3 (2025)
- 页面: 45-50
- 栏目: ORIGINAL STUDIES
- URL: https://journals.eco-vector.com/2412-4036/article/view/687160
- DOI: https://doi.org/10.18565/therapy.2025.3.45-50
- ID: 687160
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详细
Obesity is an important medical problem that significantly worsens the prognosis for life and health of the population. However, among obese individuals, there is a group that does not have metabolic complications and is characterized by moderate cardiometabolic risks. This phenotype is called “metabolically healthy obesity” (MHO). Studies of individual obesity phenotypes, MHO in particular, seems to be important in terms of optimizing approaches to the prevention and treatment such kind of patients.
The aim: to study MHO peculiarities among the population aged 45–69 in the Ryazan region.
Material and methods. Analysis included the data from 255 individuals aged 45 to 69 years with no chronic non-communicable diseases. It consisted of 78% female and 22% male patients. NCEP ATP III criteria were used to determine the metabolic health condition. MHO was assessed as a combination of body mass index ≥ 30 kg/m² and less than three criterion indexes.
Results. The prevalence of MHO according to NCEP ATP III criteria among the selected group was 101 individuals (39.6%). From them, 30 were male (53.5% among obese males) and 71 female (35.7% among obese females) individuals. MHO was fixed 1.5 times more often among male persons, p < 0.05. Among MHO individuals, two components of metabolic health disorder were found more common (84.2%) than one (15.8%). No differences were found in the frequency of occurrence of metabolic health disorder components between male and female groups (p> 0.05), as well as in the prevalence of various degrees of obesity (p > 0.05). Differences in the age groups of male and female patients are statistically insignificant (p > 0.05).
Conclusion. The data we obtained indicate a fairly high prevalence of MHO in the population, which promotes interest for a more detailed study of this group of individuals. Detailing MHO phenotype can be useful for risk stratification and personalization of approaches to prophylaxis among obesity patients with.
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作者简介
Irena Berezenko
Academician I.P. Pavlov Ryazan State Medical University of the Ministry of Healthcare of Russia
编辑信件的主要联系方式.
Email: berezenkoil@yandex.ru
ORCID iD: 0009-0000-6471-7324
MD, assistant at the Department of outpatient therapy, preventive medicine and general medical practice
俄罗斯联邦, RyazanEvgeny Filippov
Academician I.P. Pavlov Ryazan State Medical University of the Ministry of Healthcare of Russia
Email: e.philippov@rzgmu.ru
ORCID iD: 0000-0002-7688-7176
SPIN 代码: 2809-2781
MD, Dr. Sci. (Medicine), professor, head of the Department of outpatient therapy, preventive medicine and general medical practice
俄罗斯联邦, RyazanMaria Volchenkova
Academician I.P. Pavlov Ryazan State Medical University of the Ministry of Healthcare of Russia
Email: mariyasolodun@mail.ru
ORCID iD: 0000-0003-0268-0612
SPIN 代码: 2505-9190
MD, PhD (Medicine), associate professor of the Department of outpatient therapy, preventive medicine and general medical practice
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