Use of structural-modifying medicaments for lumbal pain patients


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Lumbal pain syndrome caused by degenerative vertebral column pathology is one of the most often reasons for applying for both outpatient and inpatient care; also it is one of the most common temporary disability reason. One of the basic ground for lumbal pain syndrome occuring is osteoartritis, damaging mainly the small joints of vertebral column. Modern possibilities of treatment lumbal pain patients by means of slow-acting medicaments' use (SYSADOA) for symptomatic treatment of osteoarthritis are considered. Data concerning the efficacy of medicine Artra use for lumbal pain patients are also considered.

Full Text

Restricted Access

About the authors

Pavel R. Kamchyatnov

N.I. Pirogov Russian national research medical university of the Ministry of Health of Russia

Email: pavkam7@gmail.com
MD., professor of the Department of neurology, neurosurgery and medical genetics of general medicine department

Alexandr V. Chugunov

N.I. Pirogov Russian national research medical university of the Ministry of Health of Russia

Email: chugunova-lyudmila@mail.ru
Ph.D., professor of the Department of neurology, neurosurgery and medical genetics of general medicine department

Saida B. Khanmurzaeva

Dagestan state medical university of the Ministry of Health of Russia

Email: bagavdinovna@mail.ru
Ph.D. аssistant of the Department of neurology, neurosurgery and medical genetics of general medicine department

Naida B. Khanmurzaeva

Dagestan state medical university of the Ministry of Health of Russia

Ph.D., аssistant of the Department of pharmacology

References

  1. Kim T., Montejano L., Cao Z., Zhao Y. Health care costs in US patients with and without a diagnosis of osteoarthritis. J. of Pain Res. 2012:5 23-30.
  2. Hall H., McIntosh G. Low back pain (acute) Clin Evid. 2008;2008: 1102-1108.
  3. Schneider S., Schmitt H., Zoller S., Schiltenwolf M. Workplace stress, lifestyle and social factors as correlates of back pain: a representative study of the German working population. Int Arch Occup Environ Health. 2005; 78(4):253-69.
  4. Borenstein D. Does osteoarthritis of the lumbar spine cause chronic low back pain? Curr Pain Headache Rep. 2004; 8:512-517.
  5. Schütze N. Angiogenesis in Osteoarthritis. Current Rheumatology Reviews, 2008; 4; 3:1-6.
  6. Poulet B., Staines K. New developments in osteoarthritis and cartilage biology. Current Opinion in Pharmacology 2016, 28:8-13.
  7. Гусев Е.И., Никифоров А.С., Камчатнов П.Р. Неврологические симптомы, синдромы и болезни. 2-е изд. М. Гэотар-Медика. 2014: 1040 с. [Gusev E.I., Nikiforov A.S., Kamchyatnov P.R. Neurological symptomes, syndromes and diseases. 2nd issue. M.Geotar-Medica. 2014: P.1040]
  8. Никифоров А.С., Авакян Г.Н. Неврологические осложнения остеохондроза позвоночника. Изд-во Медпрактика. 2011; 256 с. [Nikiforov A.S., Avakyan G.N. Neurological complications of spinal column osteochondrosis. Medpraktika publ.house. 2011: p.256.]
  9. Hong J., Ball P. Resolution of Lumbar Disk Herniation without Surgery. N Engl J Med. 2016; 374;16: 1654.
  10. Sharma H., Gupta R., Olivero W. et al. fMRI in patients with lumbar disc disease: a paradigm to study patients over time. J. of Pain Res. 2011:4 401-405.
  11. Qaseem A., Wilt T., McLean R., Forciea M. for the Clinical Guidelines Committee of the American College of Physicians. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. [Epub ahead of print 14 February 2017]:. doi: 10.7326/M16-2367.
  12. Hagen K., Jamtvedt G., Hilde G., Winnem M. Bed rest bad for back pain, ineffective for sciatica. The updated Cochrane Review of bed rest for low back pain and sciatica. Spine. 2005; 30:542-46.
  13. van Middelkoop M., Rubinstein S., Verhagen A., Ostelo R., Koes B., van Tulder M. Exercise therapy for chronic nonspecific low-back pain. Best Pract Res Clin Rheumatol. 2010; 24(2):193-204.
  14. Helin-Salmivaara A., Saarelainen S., Gro Nroos J. Risk of upper gastrointestinal events with the use of various NSAIDs: A case-control study in a general population. Scandinavian Journal of Gastroenterology. 2007; 42: 923-932.
  15. Becker M.C., Wang T.H., Wisniewski L., Wolski K., Libby P., Lüscher T.F., Borer J.S., Mascette A.M., Husni M.E., Solomon D.H., Graham D.Y., Yeomans N.D., Krum H., Ruschitzka F., Lincoff A.M., Nissen S.E. Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis. Am. Heart J. 2009;157(4):606-12.
  16. Huskinsson E., Berry P., Gishen P. Effects of anti-inflammatory drugs on the progression of osteoarthritis of the knee. J Rheumatol 1995; 22: 1941-1946.
  17. Dougados M. Symptomatic slow-acting drugs for osteoarthritis: what are the facts? Joint Bone Spine. 2006;73(6):606-609.
  18. Lippielo L., Grande D. In vitro chondroprotection of glucosamine and chondroitin sulfate in a rabbit model of a OA and demonstration of metabolic synergy on chondrocyte in vitro. Ann Rheum Dis. 2000; 59 (Suppl 1): 266-271.
  19. Möller I., Gharbi M., Serrano H., Barbero M., Verges J. Henrotin Y. Effect of chondroitin sulfate on soluble biomarkers of osteoarthritis: a method to analyze and interpret the results from an open-label trial in unilateral knee osteoarthritis patients. BMC Musculoskeletal Disorders. 2016; 17:416 doi: 10.1186/s12891-016-1268-4
  20. Бадокин В.В. Пути оптимизации терапии остеоартроза. Arta medica. 2007; 5 (26): 55-61. [Badokin V.V. Ways of osteoarthrosis therapy optimization. Arta medica. 2007; 5 (26): 55-61.]
  21. Michel B., Bruhlmann P., Stucki G., Uebelhart D. Chondroprotection through Chondrosulf: the Zurich study. Ann Rheum Dis 2002, 61 (Supp 1): 116-119.
  22. Lippielo L., Woodword J., Karpman D. Beneficial effect of cartilage structure modyifing agents tested in chondrocyte and rabbit instability model osteoartrosis. Arthr Rheum. 1999; 42: 256-261.
  23. Алексенко Е.Ю., Говорин А.В. Изменение показателей липидов и цитокинов крови у больных первичным остеоартрозом на фоне лечения препаратом Артра. Научно-практическая ревматология. 2011; 3: 37-40. [Alekseenko E.Ju., Govorin A.V. Change of blood lipids and cytokines' indexes in primary osteoarthrosis patients on tbe phone of Artra medicine treatment. Scientific-practical rheumatology. Arta medica. 2007; 5 (26): 55-61.]
  24. Алексеева Л.И., Чичасова Н.В., Мендель О.И. Рациональный выбор базисной терапии при остеоартрозе. Результаты открытого рандомизированного многоцентрового исследования препарата АРТРА в России. РМЖ. Ревматология. 2005; 24; 13: 1636-1641. [Alekseeva L.I., Chichasova N.V., Mendel O.I. Rational choice of basis therapy in case of osteoarthrosis. Results of open randomized multicenter research work of Artra medicine in Russia. RMJ. Rheumatology. 2005; 24; 13: 1636-1641.]
  25. Jordan K., Arden N., Doherty M. et al. EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT). Ann Rheum Dis 2003; 62: 1145-1155.
  26. The efficacy of Glucosamine and Chondroitin Sulfate in Patients with Painful Knee Osteoarthritis (OA): The Glucosamine/ Chondroitin Arthritis Intervention Trial (GAIT). 2005 ACR/ARHP Annual Sciehtific Meeting, November 12-17, San Diego, California, N 622.
  27. Register J., Rovati L., Deroisy R. Glucosamine sulfate slows-down osteoarthritis progression in postmenopausal women: pooled analysis of two large, independent randomized, placebo-controlled, double-blind, prospective 3-year trials. Ann Rheum Dis. 2002; 61 (Suppl 1): 196-201.
  28. Pelletier J.-P. Comprehensive Strategies for the Treatment of Osteoarthritis Targeting Both Symptoms and Structural Changes. Eur. Musculosceletal. Rev. Osteoarthritis. EULAR. 2009. 20-24.
  29. Leffler C., Philippi A., Leffler S. еt al. Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study. Mil Med. 1999;164(2):85-91.
  30. Чебыкин А.В. Опыт применения хондропротектора Артра у пациентов с болью в спине. Неврология, нейропсихиатрия, психосоматика. 2012; 3: 67-72. [Chebykin A.V. The experience of Artra chondroprotector use in patients with back pain. Neurology, neuropsychiatry, psychosomatics. 2012; 3: 67-72.]
  31. Wilkens P., Scheel I., Grundnes O. Effect of glucosamine on pain-related disability in patients with chronic low back pain and degenerative lumbar osteoarthritis: a randomized controlled trial. JAMA. 2010; 304(1): 45-52.
  32. Singh G., Alekseeva L., Alekseev V., Triadafilopoulos G. Glucosamine-chondroitin sulfate reduces pain, disability and NSAID consumption in patients with chronic low back pain: a large, community-based, pilot, open prospective observational study. SAT0419.
  33. Алексеева Л.А., Алексеев В.В., Баринов А.Н., Пьяных С.Н., Насонов Е.Л. Применение комбинации хондроитина сульфата и глюкозамина гидрохлорида при неспецифических болях в нижней части спины в реальной клинической практике (результаты многоцентрового исследования). Manage pain. 2015; 3: 19-25. [Alekseeva L.A., Alekseev V.V., Barinov A.N., Pjanykh S.N., Nasonov E.L. Use of combination chondroitin sulfate and glucosamine hydrochloride in case of non-specific pains in lower back area in real clinical practice (results of multi-center research work). Manage pain. 2015; 3: 19-25.]
  34. Шостак Н.А., Правдюк Н.Г., Клименко А.А., Кондрашов А.А., Егорова В.А., Швырева Н.М. Дегенеративное поражение позвоночника и боль в спине: подходы к терапии. Consilium nedicum. 2015; 15(2): 37-42. [Shostak N.A., Pravdjuk N.G., Klimenko A.A., Kondrashov A.A., Egorova V.A., Shvyryova N.M. Degenerative damage of vertebral column and back pain: approaches to therapy. Consilium nedicum. 2015; 15(2): 37-42.]

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2017 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies