Correlation between low density lipoproteins / high density lipoproteins ratio and new-onset atrial fibrillation after coronary artery bypass grafting
- Authors: Tatarintseva Z.G.1, Kosmachova E.D.1,2
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Affiliations:
- Research Institute – Regional Clinical Hospital No. 1 named after Professor S.V. Ochapovsky
- Kuban State Medical University of the Ministry of Healthcare of Russia
- Issue: Vol 10, No 4 (2024)
- Pages: 59-64
- Section: ORIGINAL STUDIES
- URL: https://journals.eco-vector.com/2412-4036/article/view/634444
- DOI: https://doi.org/10.18565/therapy.2024.4.59-64
- ID: 634444
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Abstract
Atrial fibrillation (AF) is one of the common complications after coronary artery bypass grafting (CABG) operation, with a prevalence of 20 to 30%. Rare studies have confirmed the correlation of the low-density lipoprotein/high-density lipoprotein (LDL/HDL) ratio with the incidence of postoperative AF.
The aim: to analyze the correlation between preoperative LDL/HDL ratio and new-onset AF after CABG.
Material and methods. Patients operated in the cardiac surgery department of Research Institute – Regional Clinical Hospital No. 1 named after professor S.V. Ochapovsky from July 1, 2022 to January 1, 2023 were included in the study. CABG was performed in 552 patients, 60 of whom were diagnosed with AF in the early postoperative period (group A). Sinus rhythm was recorded in 424 patients, 64 of whom were included in the comparison group (B) using a random number generator.
Results. In 60 patients (10.9%) AF developed in the early postoperative period. Univariate logistic regression analysis showed that preoperative LDL/HDL ratio was not directly associated with postoperative arrhythmia. When performing ROC analysis, the area under AUC curve for this index was 0.469 (95% confidence interval: 0.364–0.574; p = 0.054), which indicates that there is no significant correlation between examined parameter and the probability of developing atrial fibrillation after CABG.
Conclusion. Correlation between the preoperative LDL/HDL ratio and the incidence of postoperative AF was not established.
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About the authors
Zoya G. Tatarintseva
Research Institute – Regional Clinical Hospital No. 1 named after Professor S.V. Ochapovsky
Author for correspondence.
Email: z.tatarintseva@list.ru
ORCID iD: 0000-0002-3868-8061
MD, PhD (Medicine), head of the department
Russian Federation, KrasnodarElena D. Kosmachova
Research Institute – Regional Clinical Hospital No. 1 named after Professor S.V. Ochapovsky; Kuban State Medical University of the Ministry of Healthcare of Russia
Email: kosmachova_h@mail.ru
ORCID iD: 0000-0001-5690-2482
MD, Dr. Sci. (Medicine), professor, head of the Department of Therapy No. 1 of the Faculty of Advanced Training and Professional Retraining of Specialists; chief medical officer
Russian Federation, Krasnodar; KrasnodarReferences
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