Polycystic liver and kidney disease

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Resumo

Article presents two clinical observations of patients with associated polycystic liver and kidney disease. Their peculiarity is the presence of clinical manifestations of the disease, which, according to the literature data, is rare. Both cases had a family history of polycystic liver and kidney disease. Onset of illness in example No. 1 occurred at 76 years of age, in example No. 2 at 44 years of age. At the same time, a different outcome of the disease was fixed with the development of portal hypertension in the first case and the need for bisegmentotomy in the second. Both patients were included in the waiting list for liver transplantation.

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Sobre autores

Dilyara Mukhametova

Kazan State Medical University of the Ministry of Healthcare of Russia

Email: muhdilyara@gmail.com
PhD in Medicine, assistant at the Department of hospital therapy

Alfiya Odintsova

Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan

Email: odincovaa@yandex.ru
PhD in Medicine, head of the gastroenterology Department

Alexander Kirshin

Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan; Kazan (Volga region) Federal University

Email: kirshinalex80@mail.ru
head of the surgical Department No. 2; assistant at the Department of surgical diseases of postgraduate education of the Institute of fundamental medicine and biology

Aigul Kirshina

Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan

Email: aygulraisovna@gmail.com
gastroenterologist at the Department of gastroenterology

Alina Khasanshina

Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan

gastroenterologist at the Department of gastroenterology

Alina Garaeva

Kazan State Medical University of the Ministry of Healthcare of Russia

resident of the Department of hospital therapy

Iskander Mardanov

Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan

surgeon at the Department of surgery No. 2

Diana Abdulganieva

Kazan State Medical University of the Ministry of Healthcare of Russia

Email: diana_s@mail.ru
Dr. med. habil., professor, head of the Department of hospital therapy

Bibliografia

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  2. Lantinga M.A., Gevers T.J., Drenth J.P. Evaluation of hepatic cystic lesions. World J. Gastroenterol. 2013; 19(23): 3543-54. https://dx.doi.org/10.3748/wjg.v19.i23.3543.
  3. Masyuk T.V., Masyuk A.I., LaRusso N.F. Polycystic liver disease: Advances in understanding and treatment. Annu Rev Pathol. 2022; 17: 251-69. https://dx.doi.org/10.1146/annurev-pathol-042320-121247.
  4. Zhang Z.Y., Wang Z.M., Huang Y. Polycystic liver disease: Classification, diagnosis, treatment process, and clinical management. World J. Hepatol. 2020; 12(3): 72-83. https://dx.doi.org/10.4254/wjh.v12.i3.72.
  5. Neijenhuis M.K., Kievit W., Verheesen S.M. et al. Impact of liver volume on polycystic liver disease-related symptoms and quality of life. United European Gastroenterol J. 2018; 6(1): 81-88. https://dx.doi.org/10.1177/2050640617705577.
  6. Qian Q. Isolated polycystic liver disease. Adv Chronic Kidney Dis. 2010; 17(2): 181-89. https://dx.doi.org/10.1053/j.ackd.2009.12.005.
  7. Ueno T., Barri Y.M., Netto G.J. et al. Liver and kidney transplantation for polycystic liver and kidney-renal function and outcome. Transplantation. 2006; 82(4): 501-7. https://dx.doi.org/10.1097/01.tp.0000231712.75645.7a.
  8. Masyuk T.V., Masyuk A.I., LaRusso N.F. Therapeutic targets in polycystic liver disease. Curr Drug Targets. 2017; 18(8): 950-57. https://dx.doi.org/10.2174/1389450116666150427161743.
  9. Kothadia J.P., Kreitman K., Shah J.M. Polycystic liver disease. 2022. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022.

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