Evaluating processes of cardiac remodeling in the development of chronic thromboembolic pulmonary hypertension


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The aim. To evaluate the processes of remodeling of the right and left heart in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Material and methods. The study included 30 patients who underwent in-patient examination and treatment at the State Clinical Hospital №1 named after N.I. Pirogov, Moscow, to confirm the diagnosis of CTEPH and the selection of drug therapy. For all patients, one expert performed an echocardiographic (EchoCG) study to evaluate the parameters of the right and left parts of the heart. Results. Statistically significant correlations between the severity of CTEPH flow and the structural and functional parameters of the right and left parts of the heart were obtained. Conclusions. The evaluation of structural and functional echocardiographic parameters of cardiac remodeling in patients with CTEPH was performed. Correlation links between severity of the disease course and echocardiographic data are revealed, which allows a simple, non-invasive method to conduct dynamic observation of patients and to identify prognostically unfavorable factors of CTEPH course.

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作者简介

Victoria Shemenkova

Russian National Research Medical University named after N.I. Pirogov; Clinical Hospital № 1 named after N.I. Pirogov

Email: vshemenkova@mail.ru
PhD candidate of the acad. A.I. Nesterov; therapist

Nadezhda Shostak

Russian National Research Medical University named after N.I. Pirogov

Email: shostakkaf@yandex.ru
MD., professor, head of the acad. A.I. Nesterov Chair of Intermediate Level Therapy

Alesya Klimenko

Russian National Research Medical University named after N.I. Pirogov

Email: shostakkaf@yandex.ru
PhD., associate professor of the acad. A.I. Nesterov Chair of Intermediate Level Therapy

Aleksandra Bogdanova

Clinical Hospital № 1 named after N.I. Pirogov

Email: doc.aabogdanova@mail.ru
PhD, head of the Department of functional diagnostics

Darja Kotova

Russian National Research Medical University named after N.I. Pirogov; Clinical Hospital № 1 named after N.I. Pirogov

PhD., head of the Department of therapy; associate professor of acad. A.I. Nesterov Chair of Intermediate Level Therapy

参考

  1. Клинические рекомендации по диагностике и лечению хронической тромбоэмболической легочной гипертензии. Евразийский кардиологический журнал. 2016;2:7-27.
  2. Riedel M., Stanek V., Widimsky J. et al. Long-term follow-up of patients with pulmonary thromboembolism. Late prognosis and evolution of hemodynamic and respiratory data. Chest 1982;81:151-8.
  3. ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension, 2015 http://www.scardio.ru/content/ Guidelines/ESC%20_L_hypert_2015.pdf (In Russ.)
  4. Gopalan D., Blanchard D., Auger W. Diagnostic evaluation of chronic thromboembolic pulmonary hypertension. Ann Am Thorac Soc. 2016;13:222-39.
  5. Kasai H., Matsumura A., Suqiura T. et al. Mean pulmonary artery pressure using echocardiography in chronic thromboembolic pulmonary hypertension. Circ J. 2016;80(5):1259-64.
  6. Boilson B.A., Pislaru S.V., McGregor C.G. Accuracy of echocardiographic assessment of pulmonary hypertension severity and right ventricular dysfunction in patients with chronic thromboembolic pulmonary hypertension. Minerva Cardioangiol. 2012;60(3):257-65.
  7. Gruning E., Tiede H., Enyimayew E.O. et al. Assessment and prognostic relevance of right ventricular contractile reserve in patients with severe pulmonary hypertension. Circulation. 2013;128(18):2005-1 5.
  8. Grapsa J., Pereira Nunes M.C., Tan T.C. et al. Echocardiographic and hemodynamic predictors of survival in precapillary pulmonary hypertension: seven-year follow-up. Circ Cardiovasc Imaging. 2015;8(6):43-54.
  9. Ernande L., Cottin V., Leroux P.Y. et al. Right isovolumic contraction velocity predicts survival in pulmonary hypertension. J. Am Soc Echocardiogr. 2013;26(3):297-306.

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