ETIOLOGY OF SEVERE ACUTE RESPIRATORY VIRAL INFECTION DURING THE EPIDEMIC SEASONS 2015-2020


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详细

The aim of the study was to establish the contribution of separate etiological agents to the development of severe forms of acute respiratory viral infections (SARI) registered in hospital conditions depending on the age of patients during several consecutive epidemic seasons. Material and methods. A retrospective analysis of the etiology of SARI cases was carried out in 14 414 hospitalized patients included in the study on hospital surveillance of influenza in the 2015- 2020 seasons, for which a laboratory decoding of ARVI etiology was obtained. Results. The contribution of various influenza viruses to the development of SARI was determined, and the leading role of influenza A (H1N1) pdm09 viruses as a reason point for hospitalization in the intensive care unit (ICU) was shown. The role of viruses of non- influenza etiology in children’s morbidity has been demonstrated, including the importance of the respiratory syncytial virus as the leading pathogen in acute respiratory viral infections structure in young children, leading to the development of SARI with subsequent ICU hospitalization. In addition, the contribution of rhinovirus infection to the development of ARVI in patients of all age groups hospitalized with SARI of noninfluenza etiology was determined. Conclusion. Current study demonstrates the importance of continuing research in the field of hospital monitoring for influenza and other acute respiratory viral infections, especially in conditions of active circulation of the causative agent of new COViD-19 coronaviral infection.

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作者简介

Daria Danilenko

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: daria.danilenko@influenza.spb.ru
candidate of biological sciences, Deputy Director for scientific work, head of the Department of etiology and epidemiology 197376, St. Petersburg, 15/17 Professor Popov Str

Anna Sominina

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: anna.sominina@influenza
MD, professor, head of the laboratory for the study of risk factors for influenza and acute respiratory viral infections, chief researcher 197376, St. Petersburg, 15/17 Professor Popov Str

Andrey Komissarov

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: andrey.komissarov@influenza.spb.ru.com
head of the laboratory of molecular virology 197376, St. Petersburg, 15/17 Professor Popov Str

Maria Pisareva

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: maria.pisareva@influenza.spb.ru
candidate of biological sciences, leading researcher of the laboratory of molecular virology 197376, St. Petersburg, 15/17 Professor Popov Str

Kirill Stolyarov

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: kirill@influenza.spb.ru
leading programmer of the laboratory of epidemiology of influenza and acute respiratory disorders 197376, St. Petersburg, 15/17 Professor Popov Str

Tamila Musaeva

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: tamila.musaeva@influenza.spb.ru
junior researcher of the laboratory of molecular virology 197376, St. Petersburg, 15/17 Professor Popov Str

Veronika Eder

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: veronika.eder@influenza.spb.ru
senior researcher of the laboratory of molecular virology 197376, St. Petersburg, 15/17 Professor Popov Str

Mikhail Bakaev

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: mibakaev18@gmail.com
junior researcher of the laboratory of molecular virology 197376, St. Petersburg, 15/17 Professor Popov Str

Ksenia Komissarova

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: ksenia.komissarova@influenza.spb.ru
junior researcher of the laboratory of molecular virology 197376, St. Petersburg, 15/17 Professor Popov Str

Anna Ivanova

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: anna.ivanova@influenza.spb.ru
junior researcher of the laboratory of molecular virology 197376, St. Petersburg, 15/17 Professor Popov Str

Artem Fadeev

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: artem.fadeev@influenza.spb.ru
researcher of the laboratory of molecular virology 197376, St. Petersburg, 15/17 Professor Popov Str

Elizaveta Smorodintseva

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: liza.smorodintseva@influenza.spb.ru
leading researcher of the laboratory of epidemiology of influenza and acute respiratory diseases 197376, St. Petersburg, 15/17 Professor Popov Str

Elena Rozhkova

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia

Email: elena.rozhkova@influenza.spb.ru
PhD., leading researcher, Department of experimental and clinical research 197376, St. Petersburg, 15/17 Professor Popov Str

Dmitry Guzhov

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia; S.P. Botkin Clinical Infectious Diseases Hospital

Email: dimas1992@list.ru
full-time postgraduate student; infectious disease physician 191024, St. Petersburg, 3 Mirgorodskaya Str

Evgeny Venev

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia; S.P. Botkin Clinical Infectious Diseases Hospital

Email: imberbis@gmail.com
full-time postgraduate student, senior lecturer; infectious disease physician 197376, St. Petersburg, 15/17 Professor Popov Str

Elena Dondurey

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia; N.F. Filatov Children's City Clinical Hospital No. 5; Health Committee of the Government of St. Petersburg

Email: elena.dondurei@influenza.spb.ru
senior researcher of the Department of respiratory viral infections in children; head of the Department - infectious disease doctor of the infectious boxed Department No. 10; Chief freelance specialist on infectious diseases in children 192289, St. Petersburg, 134 Bukharestskaya Str

Olga Afanasieva

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia; St. Olga Children's City Hospital

Email: olga.afanasieva@influenza.spb.ru
MD, head of the Department of respiratory viral infections in children 194156, St. Petersburg, 2 Zemledeltcheskaya Str

Elena Obraztsova

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia; N.F. Filatov Children's City Clinical Hospital No. 5

Email: elena.obraztsova@influenza.spb.ru
PhD, senior researcher of the Department of respiratory viral infections in children 192289, St. Petersburg, 134 Bukharestskaya Str

Veronika Timonina

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia; St. Olga Children's City Hospital

neonatologist 194156, St. Petersburg, 2 Zemledeltcheskaya Str

Ekaterina Golovacheva

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia; St. Olga Children's City Hospital

Email: golovacheva@influenza.spb.ru
PhD, senior researcher of the laboratory for development and testing of pharmaceutical agents 194156, St. Petersburg, 2 Zemledeltcheskaya Str

Olga Kurskaya

Federal Research Center for Fundamental and Translational Medicine

Email: kurskaya_og@mail.ru
PhD, senior researcher of the laboratory for development and testing of pharmaceutical agents 630117, Novosibirsk, 2 Timakova Str

Alexander Shestopalov

Federal Research Center for Fundamental and Translational Medicine

Email: shestopalov2@ngs.ru
doctor of biological sciences, professor, head of the Department of experimental modeling and pathogenesis of infectious diseases 630117, Novosibirsk, 2 Timakova Str

Alexander Alimov

Yekaterinburg Research Institute of Viral Infections of SSC VB «Vector» of Rospotrebnadzor

Email: alexalimov@yandex.ru
PhD, Director of Yekaterinburg Research Institute of Viral Infections 620030, Yekaterinburg, 23 Letnyja Str

Evgenia Lelenkova

Yekaterinburg Research Institute of Viral Infections of SSC VB «Vector» of Rospotrebnadzor

Email: e.lelenkova@inbox.ru
epidemiologist of Yekaterinburg Research Institute of Viral Infections 620030, Yekaterinburg, 23 Letnyja Str

Dmitry Lioznov

A.A. Smorodintsev Research Institute of Influenza of the Ministry of Healthcare of Russia; Acad. I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of Russia

Email: office@influenza.spb.ru
acting director; head of the Department of infectious diseases 197376, St. Petersburg, 15/17 Professor Popov Str

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