Clinical case: interstitial pulmonary fibrosis in systemic sclerosis


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详细

The introductory part of the article provides a concise literature review on the etiology, classification, frequency and variants of systemic sclerosis (SSc). The article presents a clinical case of a 78-year-old female patient with a clinical diagnosis of SSc. She was diagnosed with interstitial pulmonary fibrosis in systemic sclerosis based on clinical manifestation, radiological and laboratory findings. The autopsy revealed interstitial pulmonary fibrosis with cellular degeneration. Histological examination demonstrated a combination of gentle collagen fibrosis with honeycombing, nonspecific interstitial pneumonia with elastic tissue, and microscopic features of secondary pulmonary arterial hypertension.

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作者简介

Alexandra Konyukova

Research Institute of Human Morphology

Email: have.to.study@yandex.ru
resident of the Laboratory of clinical morphology

Valentina Pechnikova

Research Institute of Human Morphology

Email: valiagtx@yandex.ru
pathologist, junior researcher of the Laboratory of clinical morphology

Olesya Vasyukova

Research Institute of Human Morphology

Email: lpana@yandex.ru
junior researcher of the Laboratory of clinical morphology

Lidia Ananieva

V.A. Nasonova Research Institute of Rheumatology

MD, professor, head of the Laboratory of microcirculation and inflammation

Andrey Cherniaev

Research Institute of Human Morphology; Research Institute of Pulmonology of FMBA of Russia

Email: cheral12@gmail.com
MD, professor head of the Department of fundamental pulmonology

Maria Samsonova

Research Institute of Pulmonology of FMBA of Russia; A.S. Loginov Moscow Clinical Scientific Center of the Department of Healthcare of Moscow

Email: sama-ry@mail.ru
MD, head of the Laboratory of pathological anatomy

参考

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  12. Perelas A., Arrossi A.V., Highland K.B. Pulmonary manifestations of systemic sclerosis and mixed connective tissue disease. Clin Chest Med. 2019; 40(3): 501-18. doi: 10.1016/j.ccm.2019.05.001.
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