LABORATORY INDICATORS OF DIABETIC POLYNEUROPATHY
- Authors: Stepanova TV1, Popyhova EB1, Ivanov AN1
-
Affiliations:
- Central Research Laboratory of Saratov State Medical Universitу n.a. V.I. Razumovsky, Saratov
- Issue: Vol 19, No 1S (2019)
- Pages: 112-114
- Section: Articles
- Published: 15.12.2019
- URL: https://journals.eco-vector.com/MAJ/article/view/19354
- ID: 19354
Cite item
Abstract
This study is devoted to diabetic polyneuropathy (DPN) - one of the common complications of diabetes mellitus (DM). The possibilities of laboratory diagnosis of this condition are shown. The purpose of this study was to examine the pathogenetic and diagnostic significance of certain neurospecific proteins and cytokines in DPN. The analysis of the literature data on the possibility of using neurospecific proteins and some cytokines in patients with diabetes as markers of neural tissue damage has been carried out.
Full Text
About the authors
T V Stepanova
Central Research Laboratory of Saratov State Medical Universitу n.a. V.I. Razumovsky, Saratov
E B Popyhova
Central Research Laboratory of Saratov State Medical Universitу n.a. V.I. Razumovsky, Saratov
A N Ivanov
Central Research Laboratory of Saratov State Medical Universitу n.a. V.I. Razumovsky, Saratov
References
- Kurushina ОV, Barulin AЕ, Karpukhina DV. Markers of peripheral nervous system lesion in diabetes mellitus. Medicinskij sovet. 2017;11:23-26.
- YaretsYuI, Malkov AB. Neuro-specific blood proteins in the diagnosis of preclinical forms of diabetic distal polyneuropathy. Problemy zdorov’ya i ehkologii. 2018;3:61-66.
- Li J, Zhang H, Xie M, et al. NSE, a Potential Biomarker, Is Closely Connected to Diabetic Peripheral Neuropathy. Diabetes care. 2013;36:3405-3410.
- Li R, Ma J, Wu Y, et al.Dual Delivery of NGF and bFGF Coacervater Ameliorates Diabetic Peripheral Neuropathy via Inhibiting Schwann Cells Apoptosis. Int. J. Biol. Sci. 2017;13:640-651.
- Magrinelli F, Briani C, Romano M, et al. The Association between Serum Cytokines and Damage to Large and Small Nerve Fibers in Diabetic Peripheral Neuropathy. J Diab Res. 2015;5. Article ID 547834. http://dx.doi.org/10.1155/2015/547834.
- Wilson NM, Wright DE. Inflammatory Mediators in Diabetic Neuropathy. J Diabetes Metab. 2011;S5:004. http://dx.doi.org/10.4172/2155-6156.S5-004.
- Gatckikh IV, Veselova OF, Petrova MM, et al. Role of brain-derived neurotrophic factor (bdnf) in the diagnosis of cogntive dysfunction in patients with type 2 diabetes. V mire nauchnyh otkrytij. 2016;1(73):10-23.
Supplementary files



