Email this article Sepsis and diabetes mellitus. Pathogenetic parallels and crossroads
- Authors: Eryukhin I.A.1, Shlyapnikov S.A.2
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Affiliations:
- Military Medical Academy
- Dzhanelidze Institute of Emergency Ambulance
- Issue: Vol 8, No 1 (2008)
- Pages: 223-229
- Section: Articles
- Published: 08.03.2008
- URL: https://journals.eco-vector.com/MAJ/article/view/693171
- ID: 693171
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Abstract
The pathogenetic mechanisms of septic inflammation and diabetes mellitus on systemic level (disorders of carbohydrate, lipid and protein metabolism) were reviewed in the article. Besides, the epidemiological studies of distribution of surgical infection in patients with diabetes mellitus (type II preferably) were considered. In was shown that background diabetes mellitus in patients with heavy sepsis did not affect the lethality of patients. At the same time, insulin therapy in patients with heavy sepsis to support normoglucemia decreased the lethality significantly.
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About the authors
I. A. Eryukhin
Military Medical Academy
Author for correspondence.
Email: shabanov@mail.rcom.ru
член-корреспондент РАМН
Russian Federation, St. PetersburgS. A. Shlyapnikov
Dzhanelidze Institute of Emergency Ambulance
Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg
References
- Бочоришвили В. Г. Состояние и перспективы развития сепсисологии как науки и клинической специальности//Сепсис: Тезисы III республиканской конференции. С. 4-35.
- Давыдовский ИВ. Общая патология человека. 2-е изд. М.: Медицина, 1969. 611 с.
- Дедов И И, Балаболкин М И Патогенез сахарного диабета// Мед. акад. журн. 2006. Т. 6. №3. С. 3-15.
- Ребенок ЖА. Значение гемокультуры в диагностике сепсиса // Актуальные вопросы сепсисологии. Тбилиси, 1990. Т. 1. С. 243-246.
- Baynes С., Сар/ап S., Hames Р. et al. The value of screening for diabetes in patients with skin sepsis // J. of the Royal Society of Med. 1993. Vol. 86. Р. 148-151.
- Вопе R.C., Balk R.A.B., Cerra F.B. et al. American College of Chest Physicians / Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis // Crit. Care Med. 1992. Vol. 20. № 6. Р. 864-874.
- Gestel А., Bakker J. et al. Hout Prevalence and incidence of severe sepsis in Dutch intensive care units // Crit. Care. 2004. Vol. 8. Р. Rl 53-Rl 62 (DOI 10.1186/ сс2858 http://ccforum.com/content/8/4/Rl 53
- Greenwood А. М А study of the skin in five hundred cases of diabetes // JАМА. 1927. Vol. 89. Р. 774-776.
- Marshal/ J. С., Aarts М А. From Celsus to Galen to Bone: The Illnesses, Syndromes, and Diseases of Acute lnflammation // Yearbook of Intensive care and emergency medicine / Ed. J.-L.Vincent. 2001. Springer. Р. 3-12.
- Schottmйller Н. Wesen und Behandlung der Sepsis // Verh. Dtsch. Ges. Inn. Med. 1914. Vol. 31. S. 257.
- Si/va Е., de Almeida Pedro М, Sogayar А. С. В. et al. Brazilian Sepsis Epidemiological Study (BASES study) http://ccforum.com/content/8/4/R25 l
- Van Den Berghe G., Wouters Р., Weekers F. et al. Intensive Insulin therapy in critically ill patients // N. Engl. J. Med. Vol. 345. № 19. Р. 1359-1367.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).