Stem cells in experimental and clinical medicine

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Abstract

Our paper describes a technique of cell line production from embryonic stem cells (ES-cells), embryonic germ cells (EG-cells) and embryocarcinoma stem cells (ЕС-cells). The main properties of ES-cells, EG-cells and ЕС-cells are compared. The new data on plasticity and differentiation potential of adult stem cell are analyzed. The current situation and perspectives of therapeutic cloning are considered. Therapeutic cloning is production of stem cells with genotype identical to that of a person that donated somatic nuclei for transfer. The facts are presented which fortify the necessity of a further detailed study of stem cells on biological models of human diseases before using these cells in clinical medicine.

About the authors

A. P. Dyban

Institute of Experimental Medicine, Russian Academy of Medical Sciences

Author for correspondence.
Email: medaj@eco-vector.com
Russian Federation, St. Petersburg

P. A. Dyban

Institute of Experimental Medicine, Russian Academy of Medical Sciences

Email: medaj@eco-vector.com
Russian Federation, St. Petersburg

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