Chronophysiologic approach in diagnostics, treatment and prevention of bowel bradyarrhythmia

New chronophysiologic approach to the problem of bowel regularity is proposed. Chronoenterography as a new diagnostic procedure is suggested for studying the circadian defecation rhythm. Intestinal bradyarrhythmia was discovered in about 40% of persons claimed to be healthy. The availability of the «optimal» and «pessimal» phases in the temporal structure of the circadian defecation rhythm was detected. The constipation risk was proved to depend on the defecation phase. It was shown that the «optimal» defecation phase is the main determinant of the circadian bowel regularity, as its physiological significance in this regularity is as important as 3 other factors taken together: the diet, the regimen and physical activity. The quality of life of the patients with intestinal bradyarrhythmia became almost 20 % higher after treatment. The existence of some connection between intestinal bradyarrythmia and colorectal cancer was detected. Urgent need of total screening of intestinal bradyarrhythmia is indicated, as it is a risk factor of colorectal cancer, which is leader in cancer incidence and in cancer female mortality in St. Petersburg.