Vol 2, No 3 (2004)

Influence of treating with limited doses of steams of ethanol on a transpositions MGE412 was investigated in the males from isogenic lines of Drosophila melanogaster. It was proved the phenomenon of the induction. The rates of induced transpositions was estimated. Ones was 3,79-6,89xl0~2 in comparison with control, A.k=l,84xl0x 3. It was established that alcohol made be finished either death of individuals or increase genetic variability in the posterity. It was proved that ethanol is powerful inductor of transpositions MGEs of Drosophila like other different external (temperature shock, y-irradiation) and genetic factors, the main of them are isogenization and selection

Soil bacteria rhizobia establish nitrogen-fixing symbiosis with legume plants. Mutual recognition of symbiotic partners and initiation of nodule formation occur via exchange by molecular signals secreted both by plant and bacteria. This review summarizes recent data about structural diversity, genetic control of biosynthesis and functional role of Nod-factors. The possibilities of practical application of flavonoids and Nod-factors in agriculture are discussed

Estimation of population-specific frequencies of relevant polymorphisms in normal control population remains the major prerequisite of these studies. The polymorphisms of seven genes (ACE, AGTR1, eNOS, MTHFR, MTRR, APOE) associated with some multifactorial diseases (cardiovascular diseases, diabetes) were studied by PCR-RFLP analysis in North-West population of Russia. The group consisted of unrelated individuals of middle age (25-45) (59 men and 58 women). Distribution of relevant polymorphisms frequencies for MTHFR, MTRR, APOE, eNOS and AGTR1 genes was similar in our samples compared to these ones in some and European populations (Spain and Germany). Low frequency of D/D genotype and high frequency of I/I genotype were found in Russian compared to Spain population (D/D - 29,6 and 41%, I/I - 26,1 and 15%, respectively). No significant statistical differences in distribution of ACE polymorphisms were found between Russian and Scotland populations (D/D - 31%, I/I - 20%). This population specific differences for the polymorphisms of some genes and its obvious similarity for the other ones were disclosed