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Inhibin as a reproductive biomarker. Part 1

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1. Title Title of document Inhibin as a reproductive biomarker. Part 1
2. Creator Author's name, affiliation, country Zarina K. Abdulkadyrova; Saint Petersburg State University ; Russian Federation
2. Creator Author's name, affiliation, country Elena I. Abashova; The Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott ; Russian Federation
3. Subject Discipline(s)
3. Subject Keyword(s) inhibin A; inhibin B; activin; follistatin; follicle-stimulating hormone; reproductive system; folliculogenesis; spermatogenesis
4. Description Abstract

Inhibin is one of the most important hormones of the reproductive system, which is secreted by the granulose cells of the ovary and the Sertoli cells of the testes. Inhibin regulates follicle-stimulating hormone secretion involving a negative feedback loop, participates in ovarian folliculogenesis and spermatogenesis, and has great diagnostic potential in assessing the reproductive status and treating reproductive disorders. More than 90 years have passed since the discovery of inhibin, and it is becoming increasingly clear that its action is not limited to the reproductive system, as the hormone subunits and dimers are found in many organs. Further research is needed to study physiological functions of inhibin and diagnostic possibilities of its use in modern medicine. This review examines the structure and various biological functions of inhibin, as well as its role in human reproduction.

5. Publisher Organizing agency, location Eco-Vector
6. Contributor Sponsor(s)
7. Date (DD-MM-YYYY) 08.07.2019
8. Type Status & genre Peer-reviewed Article
8. Type Type Research Article
9. Format File format
10. Identifier Uniform Resource Identifier https://journals.eco-vector.com/jowd/article/view/11478
10. Identifier Digital Object Identifier (DOI) 10.17816/JOWD68361-70
10. Identifier Digital Object Identifier (DOI) (PDF (Rus)) 10.17816/JOWD11478-11803
11. Source Title; vol., no. (year) Journal of obstetrics and women's diseases; Vol 68, No 3 (2019)
12. Language English=en ru
13. Relation Supp. Files
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
15. Rights Copyright and permissions Copyright (c) 2019 Abdulkadyrova Z.K., Abashova E.I.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.