Using of the proteins of human reproductive system in diagnostic of generative health’s disorders in couples with perinatal mortality of child

详细

Objective: to study the concentration of the specific (SAMG-2 - specific alpha-microglobulin-2) and nonspecific (SAL-2 - soluble antigens of leucocytes-2) proteins in menstrual blood and sperm in parents with perinatal losses in order to estimate the state of generative health.

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Methods: clinical, immunodiffusion analysis.

Results: the decrease of secretorial function of endometrium was determined in 56,1% of women with perinatal losses according to the level of SAMG-2 in menstrual blood. Chronic endometritis was founded in 88,2%o of women according the level of SAL-2. The decrease of sperm ’s fertility was determined in 49,3% of men according to the level of SAMG-2 in sperm. Chronic prostatitis was founded in 51,7%o of men using the examination of SAL-2 level.

Conclusions: the examination of concentration of SAMG-2 and SAL-2 in menstrual blood and sperm in parents with perinatal mortality of child is the high-informative method of diagnostic of reproductive health disorders.