The influence of fertility proteins upon lymphocyte activation in decidua
- 作者: Panova I.A.1, Sotnikova N.Y.1, Posiseeva L.V.1, Kudryashova A.V.1, Kroshkina N.V.1, Chelyshev O.L.1, Astraukh N.V.1
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隶属关系:
- Institute of Maternity and Childhood
- 期: 卷 48, 编号 5S (1999)
- 页面: 122-122
- 栏目: Articles
- ##submission.dateSubmitted##: 20.02.2022
- ##submission.dateAccepted##: 20.02.2022
- ##submission.datePublished##: 15.12.1999
- URL: https://journals.eco-vector.com/jowd/article/view/101281
- DOI: https://doi.org/10.17816/JOWD101281
- ID: 101281
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Objective: The aim of the present work was to investigate the effect of pregnancy proteins SP-I and aMGF upon parameters of activation of decidual lymphoid cells in normal pregnancy and gestosis.
全文:
Objective: The aim of the present work was to investigate the effect of pregnancy proteins SP-I and aMGF upon parameters of activation of decidual lymphoid cells in normal pregnancy and gestosis.
Method: The expression of activation markers by decidual lymphocytes of II women with normal and 10 women with gestosis was examined by flow cytomerty.
Results: It was found, that in normal pregnancy SP-I increased the expression of CD95 and decreased the expression of CD71 molecules and HLA-DR antigens. In gestosis pregnancy it diminished the expression of CD71, but enhanced the amount of HLA-DR-positive lymphocytes in decidua. Contrary to that, SAMG- 2 in normal pregnancy elevated the number of CD25+ and CDIIb+ decidual lymphocytes, but in women with gestosis it down regulated the expression of CD71 and CDIIb molecules.
Conclusions: Thus, it can be supposed that at local level SP-I in normal pregnancy suppressed the late stages of cell activation and enhanced apoptosis processes, while in gestosis it impaired both steps of lymphocyte activation in decidua. From the other hand, SAMG-2 in normal pregnancy induced cell cooperation and decreased it in gestosis pregnancy.
作者简介
I. Panova
Institute of Maternity and Childhood
编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, Ivanovo
N. Sotnikova
Institute of Maternity and Childhood
Email: info@eco-vector.com
俄罗斯联邦, Ivanovo
L. Posiseeva
Institute of Maternity and Childhood
Email: info@eco-vector.com
俄罗斯联邦, Ivanovo
A. Kudryashova
Institute of Maternity and Childhood
Email: info@eco-vector.com
俄罗斯联邦, Ivanovo
N. Kroshkina
Institute of Maternity and Childhood
Email: info@eco-vector.com
俄罗斯联邦, Ivanovo
O. Chelyshev
Institute of Maternity and Childhood
Email: info@eco-vector.com
俄罗斯联邦, Ivanovo
N. Astraukh
Institute of Maternity and Childhood
Email: info@eco-vector.com
俄罗斯联邦, Ivanovo
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