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Cytomegalovirus uveitis in HIV-infected people: possible complications
- Authors: Sizova T.D.1,2, Khokkanen V.M.2, Zumbulidze N.G.2
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Affiliations:
- Saint Petersburg Center for Control of AIDS and Infectious Diseases
- North-Western State Medical University named after I.I. Mechnikov
- Issue: Vol 15, No 1 (2022)
- Pages: 7-14
- Section: Original researches
- URL: https://journals.eco-vector.com/ov/article/view/105493
- DOI: https://doi.org/10.17816/OV105493
- ID: 105493
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Abstract
BACKGROUND: Cytomegalovirus uveitis is an AIDS-marker disease. If typical chorioretinal foci associated with cytomegalovirus viremia, inflammatory diseases of cytomegalovirus etiology of other organs are detected, etiotropic treatment and antiretroviral therapy are prescribed. Later on, the patient continues to be monitored by an ophthalmologist.
AIM: The aim is to identify the structure of complications, the frequency and the timing of their occurrence in cytomegalovirus uveitis in HIV-infected patients, the relationship with the treatment.
MATERIALS AND METHODS: The study was performed at the St. Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases and the Department of Ophthalmology of the North-Western State Medical University named after I.I. Mechnikov. The study group consisted of 66 patients (97 eyes).
RESULTS: The development of complications of the disease was detected in 86.6% of patients. In patients, following complications were reported: retinal detachment, complicated cataract, partial optic nerve atrophy, cystoid macular edema, and secondary exotropia.
CONCLUSION: Cytomegalovirus uveitis in HIV-infected patients has a predominantly complicated course.
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About the authors
Tatiana D. Sizova
Saint Petersburg Center for Control of AIDS and Infectious Diseases; North-Western State Medical University named after I.I. Mechnikov
Author for correspondence.
Email: tanja_sizova@list.ru
ORCID iD: 0000-0003-4089-1242
SPIN-code: 2939-5495
Ophthalmologist, Postgraduate Student
Russian Federation, Saint Petersburg; Saint PetersburgValentina M. Khokkanen
North-Western State Medical University named after I.I. Mechnikov
Email: valentina.khokkanen@szgmu.ru
ORCID iD: 0000-0001-8096-5088
SPIN-code: 6536-4889
Dr. Sci. (Med.), Professor, Professor of Ophthalmology Department
Russian Federation, Saint PetersburgNatalia G. Zumbulidze
North-Western State Medical University named after I.I. Mechnikov
Email: guramovna@gmail.com
ORCID iD: 0000-0002-7729-097X
SPIN-code: 4439-8855
Cand. Sci. (Med.), Associate Professor of Ophthalmology Department
Russian Federation, Saint PetersburgReferences
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