Prostaglandin analogues: past, present, and future

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Abstract


This literature review is focused on the prostaglandin topical analogues and describes peculiarities of their structure, pharmacokinetics and pharmacodynamics, results of clinical trials and meta-analyzes, as well as modern trends in the topical IOP-lowering glaucoma therapy evolution.


Yury S Astakhov

FSBEI HE “Academician I.P. Pavlov First St Petersburg State Medical University” of the Ministry of Healthcare of Russia

Author for correspondence.
Email: astakhov73@mail.ru

Russian Federation, Saint Petersburg, Russia

MD, PhD, professor. Ophthalmology Department

Pavel A Nechiporenko

FSBEI HE “Academician I.P. Pavlov First St Petersburg State Medical University” of the Ministry of Healthcare of Russia

Email: glaz@doctor.com

Russian Federation, Saint Petersburg, Russia

MD, PhD, assistant. Ophthalmology Department

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