Choroidal thickness in normal subjects and in age-related macular degeneration
- 作者: Astakhov Y.S.1, Belekhova S.G.1, Dal N.Y.1
-
隶属关系:
- I. P. Pavlov State Medical University of St. Petersburg
- 期: 卷 7, 编号 1 (2014)
- 页面: 4-7
- 栏目: Articles
- ##submission.dateSubmitted##: 24.06.2015
- ##submission.datePublished##: 15.03.2014
- URL: https://journals.eco-vector.com/ov/article/view/421
- DOI: https://doi.org/10.17816/OV201414-7
- ID: 421
如何引用文章
全文:
详细
Results of choroidal thickness measurements in 75 healthy subjects of different age groups (123 eyes) are presented as well as those of 35 patients (45 eyes) with age-related macular degeneration. Examinations were performed with a Spectralis optical coherence tomograph using the regimen of Enhanced Depth Imaging (EDI-OCT). A negative dependence between choroidal thickness and age was found (r = -0.78, p < 0.0001). Sub-foveal thickness of the choroid decreases on average by 2.99 µm for every life year. No significant differences in choroidal thickness of age-related macular degeneration patients and that of healthy people of the same age group were found.
作者简介
Yuriy Astakhov
I. P. Pavlov State Medical University of St. Petersburg
Email: astakhov73@mail.ru
MD, doctor of medical science, professor, head of the department of ophthalmology
Svetlana Belekhova
I. P. Pavlov State Medical University of St. Petersburg
Email: beleksv@yandex.ru
Postgraduate student. Department of Ophthalmology
Nikita Dal
I. P. Pavlov State Medical University of St. Petersburg
Email: ndahl@yandex.ru
candidate of medical science, assistant professor. Department of Ophthalmology
参考
- Астахов Ю. С., Лисочкина А. Б., Шадричев Ф. Е. Возрастная макулярная дегенерация // Клинические рекомендации. Офтальмология / под ред. Л. К. Мошетовой, А. П. Нестерова, Е. А. Егорова. - М.: ГЭОТАР-Медиа, 2006. - 164 с.
- Улитина А. Ю., Измайлов А. С. Оценка толщины хориоидеи при возрастной макулярной дегенерации // Вестник ОГУ. - 2013. - № 4 (153). - 275-279 с.
- Chung S. E., Kang S. E., Lee J. H., Kim Y. T. Choroidal thickness in polypoidal choroidal vasculopathy and exudative age-related macular degeneration // Ophthalmology. - 2011. - Vol. 118, N 5. - P. 840-845.
- Donald J., Gass M., 1977.
- Fujiwara T., Imamura Y., Margolis R., Slakter J. S. et al. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes // Am. J. Ophthalmol. - 2009. - Vol. 148, N 3. - P. 445-450.
- Grunwald J., Metelitsina T., DuPont J., Ying G-S., Maguire M. Reduced foveolar choroidal blood flow in eyes with increasing AMD severity // Invest. Ophthalmol. Vis Sci. - 2005. - Vol. 46. - P. 1033-1038.
- Huang D., Swanson E. A., Lin C. P., Schuman J. S., Stinson W. G., Chang W., Hee M. R., FlotteT., GregoryK., PuliafitoC. A., Fujimoto J. G. Optical coherence tomography // Science. - 1991. - Vol. 254 - P. 1178-81.
- Imamura Y., Fujiwara T., Margolis R., Spaide R. F. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy // Retina. - 2009. - Vol. 28. - P. 1469-1473.
- Jonas J. B., Forster T. M., Steinmetz P., Schlichtenbrede F. C., Harder B. C. Choroidal thickness in age-related macular degeneration //Retina. - 2013.
- Klein R., Klein B. E., Jensen S. C., Cruickshanks K. J. The relationship of ocular factors to the incidence and progression of age-related maculopathy // Arch. Ophthalmol. - 1998. - Vol. 116. - P. 278-282.
- Margolis R., Spaide R. F. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes // Am. J. Ophthalmol. - 2009. - Vol. 147, № 5. - P. 811-815.
- McCourt E. A., Cadena B. C., Barnett C. J., Ciardella A. P. et al. Measurement of subfoveal choroidal thickness using spectraldomain optical coherence tomography // Ophthalmic Surg. Lasers Imaging. - 2010. - Vol. 41. - P. 28-33.
- Povazay B., Hermann B., Unterhuber A. et al. Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients //J. Biomed Opt. - 2007. - Vol. 12, N 4. - 041211.
- Stefansson E, Geirsdottir A, Sigurdsson H. Metabolic physiology in age related macular degeneration // Prog. Retin. Eye Res. - 2011. - Vol. 30. - P. 72-80.