About pathochemical changes of the system of metabolic homeostasis in acute period of ischemic stroke
- Issue: Vol 18, No 4 (2010)
- Pages: 114-118
- Section: Articles
- Submitted: 28.10.2016
- Published: 15.12.2010
- URL: https://journals.eco-vector.com/pavlovj/article/view/5182
- DOI: https://doi.org/10.17816/PAVLOVJ20104114-118
- ID: 5182
Cite item
Full Text
Abstract
Pathochemical and compensatory metabolic reactions were investigated in 30 patients with acute ischemic stroke. There were estimated blood concentration of malone dialdehyde and middle-mass endotoxic molecules and semicarbozide-sensitive amine oxidae activity. On the 5-7th days of the disease there were revealed significant increase of malone dialdehyde and middle-mass endotoxic molecules concentrations. In is possible to suppose that simultaneous changes of system semicarbozide-sensitive amine oxidae activity/ malone dialdehyde as a compensatory reaction directed to the support of metabolic homeostasis.
References
- Волошина О.Н. Метод определения активности тромбоцитарной моноаминоксидазы. /Волошина О.Н., Москвитина Т.А. // Лаб. дело. 1985. № 5- С. 289-291.
- Гусев, Е. И. Ишемия головного мозга / Е. И. Гусев, В. И. Скворцова. - М.: Медицина, 2001. - С. 13-14.
- Узбеков, М. Г. Неспецифический синдром эндогенной интоксикации как интегральный компонент патогенеза психических расстройств. / Узбеков, М. Г., Мисионжник Э. Ю. // Рос психиат журн. - 2000. - № 4. - С. 56-65.
- Узбеков М.Г. Нарушение активности моноаминоксидазы и показателей эндогенной интоксикации больных с первым эпизодом шизофрении. / Узбеков, М. Г., Мисионжник Э. Ю., Шмуклер А.Б., и др. // Журн неврол и психиат. - 2009. - № 5. - С. 173-178.
- Brott, T.G. Urgent therapy for stroke, I: Pilot study of tissue plasminogen activator administered within 90 minutes. / Brott, T.G. // Stroke. - 1992. - № 23. - Р. 632-640.
- Chen K. Sequential neuronal and astrocytic changes after transient middle cerebral artery occlusion in the rat./Chen H., Chopp M., Schultz L. // J. Neurotoxicol. - 2004. - №25. - Р. 31-36.
- Frankel M. R. Predicting prognosis after stroke: a placebo group analysis from the National Institute of Neurological Disorders and Stroke rt-PA Stroke Trial. /Frankel M. R , Morgenstern L. B., Kwiatkowski T., et al. // Neurology. - 2000. - №55. - Р. 952-959.
- Holschneider P Lack of Protection from Ischemic Injury of Monoamine Oxidase B- Deficient Mice Following Middle Cerebral Artery Occlusion.//Нolschneider, D.P., Scremin, O.U. Huynh, L., et al. //Neurosci. Letters.- 1999 <http://www.sciencedirect.com/science/journal/03043940>. - №3 - Р. 161-164
- Mahoney F. Functional evaluation: the Barthel Index/ Mahoney F., Barthel D.// MD State Med. J. 1965.- № 14- Р. 61-65.
- Maher P. The Role of Monoamine Metabolism in Oxidative Glutamate Toxicity./ Maher P., Davis J. B. // J of Neuroscie., 1996.- № 20- Р. 6394-640116
- Saura, J. Molecular neuroanatomy of human monoamine oxidase A and В revealed by quantitative enzyme radioautography and in situ hydridization hiatochemistry /J. Saura, Z. Bleuel,// J. Ulrich et al. Neuroscience. -1996. Vol. 70, №3 - Р. 755-774
- Shaheen A.A. Influence of verapamil on. the efficacy of vitamin E in preventing the ischemia-reperfusion induced bio- chemical dearrangement in cerebral cortex of rat /Shaheen A.A., Abd-el-Fattah A.A., Seif-el-Nasr M. // Arzneimittelforschung.-2008.- № 58 (4)- Р. 160-167
- Stahi S.M. The human platelets. A diagnostic and research tool for the stady of biogene amines in psychiatric and neurological disordes./ . Stahi S.M. // Arch Gen Psychiat.- 1977.-№ 34-Р. 509-517.