CNS defeat in early congenital syphilis


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Abstract

Early congenital syphilis, in 60 % of cases, accompanied by a specific lesion of the central nervous system. Clinical manifestations of neurosyphilis in newborns are usually absent. Diagnosis is based on serological examination of cerebrospinal fluid and MRI. The paper presents two cases of early syphilis with central nervous system.

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About the authors

Tamara Vladimirovna Melashenko

Saint-Petersburg State Pediatric Medical University

Email: venerology@mail.ru
Neurologist ICU Neonatal Clinic

Irina Romanovna Milyavskaya

Saint-Petersburg State Pediatric Medical University

Email: venerology@mail.ru
MD, PhD, Associate Professor, Department of Dermatology and Venereology.

Igor Aleksandrovich Gorlanov

Saint-Petersburg State Pediatric Medical University

Email: venerology@mail.ru
MD, PhD, Dr Med Sci, Professor, Head of Department of Dermatology and Venereology

Larisa Mikhaylovna Leina

Saint-Petersburg State Pediatric Medical University

Email: venerology@mail.ru
MD, PhD, Associate Professor, Department of Dermatology and Venereology

References

  1. Катаева И. В., Фриго Н. В., Лесная Г. Л. Анализ заболеваемости и качества лабораторной диагностики нейросифилиса в Российской Федерации // Вестник дерматологии и венерологии. - 2011. - № 3. - С. 18.
  2. Фриго Н. В., Катунин Г. Г., Ротанов С. В. Современные иммунологические методы исследования цереброспинальной жидкости у больных нейросифилисом // Вестник дерматологии и венерологии. - 2011. - № 6. - С. 49.
  3. Barkowich A. J. Ped. Neuroimaging // 3th ed. Philadelphia: Lippincott Williams@Wilkins. - 2005. - P. 932.
  4. Conde-Sendin M. A., Hernander-Fleta J. L., Cordenes-Santana M. A. et al. Neurosyphilis: forms of presentation and clinical management // Rev. Neurol. - 2002. - Vol. 35 (4). - P. 380-386.
  5. Herremans T. A., Geek Kort L., Notermans D. W. Review of diagnostic tests for congenital syphilis in newborn // Eur. J. Clin. Microbiol. Infect. Dis. - 2010. - Vol. 29 (5) - P. 495.
  6. Silva S., Raquel Henriques, JoA`o Paulo Gomes et al. Could we miss congenital neurosyphilis? // The Lancet infections Diseases. - 2012. - Vol. 12. - P. 816.
  7. Talati A. J., Koneru P. Neonates at risk for congenital syphilis: radiographic and cerebrospinal fluid evalutions // South Med. J. - 2011. - Vol. 104 (12). - P. 827-830.
  8. Tikhonova L. Congenital Syphilis in the Russian Federation: magnitude, determinats and consequences //Sexually Transmitted infections. - 2003. - Vol. 79 (2). - P. 67.
  9. Volpe J. J. Neurology of the Newborn // WB “Saunders”. - Philadelphia. - 2001. - P. 217-497.
  10. Wolf B., Kalanger K. Congenital neurosyphilis revisited // Eur. Journal Pediatr. - 1993. - Vol. 152. - P. 493-495.

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Copyright (c) 2014 Melashenko T.V., Milyavskaya I.R., Gorlanov I.A., Leina L.M.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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