The concept of placental insuffisiency

The authors propose classification of placental insufficiency, based on the fact that the placenta, as a provisory organ, has an exclusive ability to develop compensatory processes to be present during the whole pregnancy. The authors established the role of placental barriers, in particular the syncytiocapillary membranes, in developing placental insufficiency. The Immunohistochemical methods allow us to detect the presence of antigens and different classes of immunoglobulins on the membranes. Dystrophic and necrobiotic changes in the syncytiocapillary membranes increase the permeability of the placental barrier and contribute to the penetration of specific antibodies and pathogenic antigens to foetal organs. The risk of intrauterine infections of the foetus increases sharply if the woman has suffered a respiratory infection during pregnancy.

placenta, barrier, failure, immunohistochemical study