Embryonic development and the structure of the growth plate

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Abstract

This article presents modern data on embryonic development and zonal structure of the meta-epiphyseal growth plate in which dysfunction has an important role in the formation of skeletal deformities in children.

About the authors

Vladimir Ivanovich Zavarukhin

The Turner Institute for Children’s Orthopedics, Saint-Petersburg

Author for correspondence.
Email: zavarukhin.md@gmail.com
MD, research associate of the department of reconstructive microsurgery and hand surgery. The Turner Scientific and Research Institute for Children’s Orthopedics. Russian Federation

Ekaterina Sergeevna Morenko

The Turner Institute for Children’s Orthopedics, Saint-Petersburg

Email: emorenko@gmail.com
resident The Turner Scientific and Research Institute for Children’s Orthopedics. Russian Federation

Maxim Konstantinovich Sviridov

The Turner Institute for Children’s Orthopedics, Saint-Petersburg

Email: mksviridov@mail.ru
MD, PhD student of the department of reconstructive microsurgery and hand surgery. The Turner Scientific and Research Institute for Children’s Orthopedics. Russian Federation

Anton Vladimirovich Govorov

The Turner Institute for Children’s Orthopedics, Saint-Petersburg

Email: agovorov@yandex.ru
MD, PhD, research associate of the department of reconstructive microsurgery and hand surgery. The Turner Scientific and Research Institute for Children’s Orthopedics. Russian Federation

References

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  7. Horton J, Bariteau J, et al. Ontogeny of skeletal maturation in the juvenile rat. Anat. Rec (Hoboken). 2008;291(3):283-292. doi: 10.1002/ar.20650.
  8. Anenisia Coelho de Andrade. Local regulation of growth plane chondrocytes: molecular mechanisms and implications for longitudinal bone growth. Thesis for doctor degree (Ph. D). 2010.
  9. Ballock R, Regis J. The biology of the growth plane. JBJS. ORG. 2003;85(4):715-726.
  10. Villemure I, Stokes A. Growth plane mechanics and mechanobiology. A survey of present understanding. The Journal of biomechanics. 2009;42:1793-1803. doi: 10.1016/j.biomech.2009.05.021.
  11. Abad V, Meyers J, Weise M, et al. The role of resting zone in growth plane chondrogenesis. Endocrinology. 2002;43(5):1851-1857. doi: 10.1210/en.1435.1851.
  12. Nowlan N, Sharpe J, Prendergast P, et al. Mechanobiology of embryonic skeletal development: insights from animal models. Birth defects Rec C Embryo Today. 2010;90(3):203-213. doi: 10.1002/bdrc.20184.
  13. Myllyharju J. Extracellular matrix and developing growth plane. Curr osteoporos rep. 2014;12:439-445. doi: 10.1007/s11914-014-0232-1.
  14. Заварухин В.И., Баиндурашвили А.Г., Говоров А.В. Брахиметакарпия: особенности патологии и ее оперативного лечения. // Травматология и ортопедия России. 2013;4(70):33-41. [Zavarukhin VI, Baindurashvili AG, Govorov AV. Brakhimetakarpiya: osobennosti patologii I ee operativnogo lecheniya. Travmatologiya I ortopediy Rossii. 2013;4(70):33-41.]

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Copyright (c) 2015 Zavarukhin V.I., Morenko E.S., Sviridov M.K., Govorov A.V.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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