Metastases of Melanoma of the Skin in the Gallbladder (A Rare Clinical Case)
- 作者: Kurkov A.А.1, Sigua B.V.1, Kleymyuk S.V.1, Lataria E.L.1, Belyaeva A.V.1, Vinnichuk S.А.1, Zemlianoi V.P.1
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隶属关系:
- North-Western State Medical University named after I.I. Mechnikov
- 期: 卷 17, 编号 1 (2025)
- 页面: 98-105
- 栏目: Case report
- ##submission.dateSubmitted##: 23.06.2024
- ##submission.dateAccepted##: 09.09.2024
- ##submission.datePublished##: 13.05.2025
- URL: https://journals.eco-vector.com/vszgmu/article/view/633678
- DOI: https://doi.org/10.17816/mechnikov633678
- EDN: https://elibrary.ru/SRMMWT
- ID: 633678
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详细
Melanoma is a highly malignant tumor with a tendency to early and aggressive metastasis. Melanoma metastases in the gallbladder are found in 20% of patients with melanoma according to autopsy data, however, intravital detection of metastases is a rare case in clinical practice, which is associated with the asymptomatic course of the disease in 85% of patients. The prognosis for detecting a secondary lesion of the gallbladder in melanoma is extremely unfavorable due to late diagnosis and the high probability of concomitant metastasis. The key to prolonging survival of these patients is early detection of metastases and initiation of immediate and radical treatment. The presented clinical observation demonstrates an example of identifying metastasis of skin melanoma to the gallbladder after a two-year remission of the disease. As in most cases, the course of the disease was asymptomatic, and the reason for planned surgical treatment was the formation of the gallbladder, presumably a polyp or a conglomerate of stones, which were identified by computed tomography. Metastasis of skin melanoma to the gallbladder was confirmed by pathohistological examination of the surgical material. In patients with a history of melanoma, a thorough examination of the hepatobiliary tract should be carried out using the most informative diagnostic techniques for the timely detection of metastatic foci.
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作者简介
Alexey Kurkov
North-Western State Medical University named after I.I. Mechnikov
Email: dok.kurkov@gmail.com
ORCID iD: 0000-0002-2128-8651
SPIN 代码: 6396-4386
MD, Cand. Sci. (Medicine)
俄罗斯联邦, Saint PetersburgBadri Sigua
North-Western State Medical University named after I.I. Mechnikov
Email: dr.sigua@gmail.com
ORCID iD: 0000-0002-4556-4913
SPIN 代码: 5571-8893
MD, Dr. Sci. (Medicine)
俄罗斯联邦, Saint PetersburgSofya Kleymyuk
North-Western State Medical University named after I.I. Mechnikov
编辑信件的主要联系方式.
Email: sofikleim@gmail.com
ORCID iD: 0009-0001-1362-7916
MD
俄罗斯联邦, Saint PetersburgElgudzha Lataria
North-Western State Medical University named after I.I. Mechnikov
Email: Elguja.Lataria@szgmu.ru
ORCID iD: 0000-0002-9569-8485
SPIN 代码: 7376-9672
MD, Cand. Sci. (Medicine), Assistant Professor
俄罗斯联邦, Saint PetersburgAnna Belyaeva
North-Western State Medical University named after I.I. Mechnikov
Email: Anna.Belyaeva@szgmu.ru
ORCID iD: 0000-0002-6299-2856
SPIN 代码: 8205-6112
MD, Cand. Sci. (Medicine)
俄罗斯联邦, Saint PetersburgSergey Vinnichuk
North-Western State Medical University named after I.I. Mechnikov
Email: s.a.vinnichuk@gmail.com
ORCID iD: 0000-0002-9590-6678
SPIN 代码: 6448-9110
MD, Cand. Sci. (Medicine)
俄罗斯联邦, Saint PetersburgViacheslav Zemlianoi
North-Western State Medical University named after I.I. Mechnikov
Email: zeml.spb@mail.ru
ORCID iD: 0000-0003-2329-0023
SPIN 代码: 5398-3460
MD, Dr. Sci. (Medicine), Professor, Honored Doctor of the Russian Federation
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