The applicability of cardiopulmonary exercise testing of young obese adults

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

BACKGROUND: Obesity is an independent risk factor for cardiovascular disease. In this regard, the early detection of cardio-vascular disfunction among young adults is an important issue. This problem can be solved by the cardiopulmonary exercise testing.

AIM: The aim of this study is to determine the applicability of cardiopulmonary exercise testing to assess the functional cardiovascular state in young and obese adults.

MATERIALS AND METHODS: 84 young participants (18–44 years), 39% men, underwent a comprehensive examination including anthropometry, spirometry and cardiopulmonary exercise testing using a graded protocol in the period 2021–2022. Four groups of cardiopulmonary exercise testing indicators were assessed: metabolic, cardiovascular, ventilatory and pulmonary gas exchange parameters.

RESULTS: 35 participants (42%) were obese, 36 participants (43%) were smokers. The obesity had a negative impact on cardiovascular parameters of cardiopulmonary exercise testing: relative oxygen pulse on maximum load (60% vs. 72%, p = 0.004), heart rate on maximum load (86% vs. 90%, p = 0.024), maximum systolic blood pressure (181 mmHg vs. 156 mmHg, p < 0.001) and maximum diastolic blood pressure (92 mmHg vs. 83 mmHg, p = 0.040).

CONCLUSIONS: Cardiopulmonary exercise testing, especially assessing cardiovascular parameters, in young adults is in high practical interest for the functional cardiovascular status examination of individuals with obesity, smokers, and, particularly, in the case of their combination.

Full Text

Restricted Access

About the authors

Petr A. Kelekhsaev

Pirogov Russian National Research Medical University; Federal Research Center of Nutrition, Biotechnology and Food Safety

Author for correspondence.
Email: kelehsaevp@gmail.com
ORCID iD: 0000-0003-1167-7503
SPIN-code: 3502-7711
Russian Federation, Moscow; Moscow

Yurgita R. Varaeva

Federal Research Center of Nutrition, Biotechnology and Food Safety

Email: yurgitavaraeva@gmail.com
ORCID iD: 0000-0002-5274-2773
SPIN-code: 5825-5778
Russian Federation, Moscow

Oxana A. Kislyak

Pirogov Russian National Research Medical University

Email: kisliakoa@mail.ru
ORCID iD: 0000-0002-2028-8748

MD, Dr. Sci. (Medicine)

Russian Federation, Moscow

Antonina V. Starodubova

Pirogov Russian National Research Medical University; Federal Research Center of Nutrition, Biotechnology and Food Safety

Email: avs.ion@yandex.ru
ORCID iD: 0000-0001-9262-9233
SPIN-code: 3538-6196

MD, Dr. Sci. (Medicine)

Russian Federation, Moscow; Moscow

References

  1. World Health Organization. WHO acceleration plan to stop obesity. World Health Organization. 2023. 20 p. [cited 2024 Dec 13]. Available from: https://www.who.int/publications/i/item/9789240075634
  2. Martinchik AN, Laikam KE, Kozyreva NA, et al. The prevalence of obesity in various socio-demographic groups of the population of Russia. Problems of Nutrition. 2021;90(3):67–76. EDN: LELEYO doi: 10.33029/0042-8833-2021-90-3-67-76
  3. Blüher M. Metabolically healthy obesity. Endocr Rev. 2020;41(3):bnaa004. doi: 10.1210/endrev/bnaa004
  4. Dwivedi AK, Dubey P, Cistola DP, Reddy SY. Association between obesity and cardiovascular outcomes: updated evidence from meta-analysis studies. Curr Cardiol Rep. 2020;22(4):25. doi: 10.1007/s11886-020-1273-y
  5. Cauwenberghs N, Sente J, Van Criekinge H, et al. Integrative interpretation of cardiopulmonary exercise tests for cardiovascular outcome prediction: a machine learning approach. Diagnostics (Basel). 2023;13(12):2051. doi: 10.3390/diagnostics13122051
  6. Glaab T, Taube C. Practical guide to cardiopulmonary exercise testing in adults. Respir Res. 2022;23(1):9. doi: 10.1186/s12931-021-01895-6
  7. Neder JA. Cardiopulmonary exercise testing applied to respiratory medicine: Myths and facts. Respir Med. 2023;214:107249. doi: 10.1016/j.rmed.2023.107249
  8. Mazaheri R, Schmied C, Niederseer D, Guazzi M. Cardiopulmonary exercise test parameters in athletic population: A review. J Clin Med. 2021;10(21):5073. doi: 10.3390/jcm10215073
  9. Lim ZX, Gyanwali B, Soh J, et al. The potential benefits of assessing post-cardiopulmonary exercise testing (CPET) in aging: a narrative review. BMC Sports Sci Med Rehabil. 2023;15(1):68. doi: 10.1186/s13102-023-00671-x
  10. Piepoli MF, Corrà U, Agostoni P. Cardiopulmonary exercise testing in patients with heart failure with specific comorbidities. Ann Am Thorac Soc. 2017;14(S1):S110–S115. doi: 10.1513/AnnalsATS.201610-803FR

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1. Evaluation of the level of physical fitness among young adults, based on the presence or absence of obesity

Download (96KB)
3. Fig. 2. Correlation between maximum load oxygen pulse rate to the predicted (O2-pulsemax/pred) and body mass index (BMI) (а), number of cigarettes smoked per day (b)

Download (194KB)

Copyright (c) 2024 Eco-Vector

License URL: https://eco-vector.com/for_authors.php#07

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 71733 от 08.12.2017.