Email this article Current possibilities of predicting the development of pre-diabetes and type 2 diabetes mellitus
- Authors: Petrankov K.V.1, Salukhov V.V.1, Pugachev M.I.1, Dobrovolskaya L.M.1, Stepanova T.V.1, Izilyaeva E.A.1, Shustov S.B.1
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Affiliations:
- Kirov Military Medical Academy
- Issue: Vol 13, No 3 (2021)
- Pages: 31-42
- Section: Reviews
- URL: https://journals.eco-vector.com/vszgmu/article/view/81188
- DOI: https://doi.org/10.17816/mechnikov81188
- ID: 81188
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Abstract
Type 2 diabetes mellitus is a serious chronic disease that poses a serious public health problem since this pathology has a significant impact on health due to the high risk of occurrence and development of severe complications, which directly affects the socio-economic well-being of the population. The presented article analyzes the most significant links in the pathogenesis of type 2 diabetes mellitus, which makes it possible to determine the risk factors for its occurrence and development. The influence of obesity on disorders of carbohydrate metabolism, as well as other associated metabolic conditions, such as atherosclerosis, hypertension, dyslipidemia, has been emphasized. Anthropometric parameters and various indices are presented, allowing them to be assessed in relation to metabolic changes. The review summarizes the most convincing biochemical markers that have prognostic value in relation to the development of pre-diabetes and type 2 diabetes mellitus. The article pays special attention to the analysis and evidence base of the existing scales for assessing the risk of developing pre-diabetes and type 2 diabetes mellitus, including the first domestic calculator based on the DIARISK questionnaire. In addition, the article presents statistical data on the higher incidence of metabolic syndrome in people professionally associated with high psychoemotional load. However, the methods for assessing the risk of pre-diabetes and T2DM do not reflect the contribution of this factor to the development of carbohydrate metabolism disorders.
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About the authors
Kirill V. Petrankov
Kirov Military Medical Academy
Author for correspondence.
Email: petrankovk@yandex.ru
ORCID iD: 0000-0001-7244-4303
graduate student at the 1st Department of Internal Medicine Postgraduate Training in endocrinology
Russian Federation, 6 Akademika Lebedeva St., Saint Peterburg, 194044Vladimir V. Salukhov
Kirov Military Medical Academy
Email: vlasaluk@yandex.ru
ORCID iD: 0000-0003-1851-0941
SPIN-code: 4531-6011
MD, Dr. Sci. (Med.)
Russian Federation, 6 Akademika Lebedeva St., Saint Peterburg, 194044Maxim I. Pugachev
Kirov Military Medical Academy
Email: kenig.max@mail.ru
MD, Cand. Sci. (Med.)
Russian Federation, 6 Akademika Lebedeva St., Saint Peterburg, 194044Larisa M. Dobrovolskaya
Kirov Military Medical Academy
Email: larisadobrovoskaja@mail.ru
MD, Cand. Sci. (Med.)
Russian Federation, 6 Akademika Lebedeva St., Saint Peterburg, 194044Tatyana V. Stepanova
Kirov Military Medical Academy
Email: stepanovatatyana1998@gmail.com
ORCID iD: 0000-0001-7177-2575
SPIN-code: 3580-0596
6th year cadet
Russian Federation, 6 Akademika Lebedeva St., Saint Peterburg, 194044Elizaveta A. Izilyaeva
Kirov Military Medical Academy
Email: izi_li55@bk.ru
the cadet
Russian Federation, 6 Akademika Lebedeva St., Saint Peterburg, 194044Sergej B. Shustov
Kirov Military Medical Academy
Email: sbs5555@mail.ru
профессор 1 кафедры (терапии усовершенствования врачей) доктор медицинских наук, профессор, Заслуженный врач Российской Федерации
Russian Federation, 6 Akademika Lebedeva St., Saint Peterburg, 194044References
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).