The role of histone modifications and DNA methylation in renal cell carcinoma development



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Abstract

Epigenetic mechanisms of gene regulation play a key role in carcinogenesis. This review will focus on the recent advances of epigenetic investigations in the development of human cancer. The role of histone modifications, genomic imprinting and DNA methylation in renal cell carcinoma development and progression will be considered.

About the authors

Lilia R Kutlyeva

Institute of Biochemistry and Genetics, Ufa Research Scientific Center RAS, Ufa, Republic of Bashkortostanб RF

Email: mingazovaliliya@mail.ru Ufa

Irina R Gilayzova

Institute of Biochemistry and Genetics, Ufa Research Scientific Center RAS, Ufa, Republic of Bashkortostanб RF

Email: gilyasova_irina@mail.ru Ufa

Rita I Khusainova

Institute of Biochemistry and Genetics, Ufa Research Scientific Center RAS, Ufa, Republic of Bashkortostanб RF

Email: ritakh@mail.ru

Elsa K Khusnutdinova

Institute of Biochemistry and Genetics, Ufa Research Scientific Center RAS, Ufa, Republic of Bashkortostanб RF

Email: ekkh@anrb.ru

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