Vol 10, No 3 (2012)

Articles

IMPACT OF PARENTS GENETIC DIVERGENCE ON HETEROSIS OF F1-HYBRIDS OF SPRING TRITICALE

Orlovskaya O.A., Koren L.V., Khotyleva L.V.

Abstract

Molecular heterogeneity was studied in 20 spring triticale accessions by using ISSR- and RAPD-markers, which allowed the studied material to be grouped according to the degree of genetic relationship and to choose genetically distant parental pairs for crosses to obtain heterotic hybrids. Expression of heterosis of F1 triticale hybrids was studied. Evaluation of the degree of parents genetic divergence on the heterosis level of F1-hybrids revealed that increase of genetic distance values between parental components leads to higher probability of obtaining heterotic hybrids.
Ecological genetics. 2012;10(3):3-9
pages 3-9 views

GENETIC VARIABILITY AND POPULATION DIFFERENTIATION OF OPISTHORCHIS FELINEUS (TREMATODA) FROM WEST SIBERIA RIVERS

Zhigileva O.N., Zenovkina D.V., Zamyatina T.A.

Abstract

Genetic variability in Opisthorchis felineus from 6 Western Siberia rivers was studied using allozyme and multilocus DNA markers. Genetic subdivision of populations and the spatial genetic variability in O. felineus maritas were found to be the same when using two methods of analysis, but differed from these indices in metacercariae. Metacercariae from ide, dace and roach were not genetically different, indicating the absence of hostal subpopulations of the parasite. Low level of O. felineus genetic variability is not consistent with a pronounced population structure of intermediate hosts — Cyprinid fish.
Ecological genetics. 2012;10(3):10-16
pages 10-16 views

The level of genetic diversity and differentiation of mountain hare Lepus timidus population in Karelia

Topchieva L.V., Belkin V.V., Rendakov N.L., Malysheva I.E., Kolomeychuk S.N.

Abstract

The level of genetic diversity of mountain hare Lepus timidus was assessed in Karelia for the first time. A significant remainder was revealed after substraction of Но value from Не, which value indicates the predominant selection of homozygotes rather than heterozygotes and the occurrence of inbreeding in the groups under study. The Fst value equal to 0.133 was calculated for the animals from different regions and indicates their genetic differentiation, which allows distinguishing subpopulation groups in mountain hare population.
Ecological genetics. 2012;10(3):17-21
pages 17-21 views

ECOLOGICAL AND GENETIC ANALYSIS OF POPULATION STRUCTURE OF POPULUS TREMULA L.IN PERM REGION

Svetlakova Т.N., Boboshina I.V., Boronnikova S.V., Nechaeva J.S.

Abstract

The wide geographical and ecological distribution of aspens (Populus tremula L.) indicates its high adaptive potential. The ISSR-analysis of DNA polymorphisms in seven natural populations of Populus tremula L. (in the Perm region) was performed. Total of 119 bands were obtained of which 87 (73.1 %) were polymorphic. Seven natural populations of P. tremula possess different levels of genetic diversity, and there was a high level of genetic differentiation between the populations (GST = 0,550). The results of the study are promising for development of further programs of cultivation and preservation of valuable deciduous tree species.
Ecological genetics. 2012;10(3):22-27
pages 22-27 views

Interaction between transcriptional factors and phytohormones in regulation of plant meristems activity

Tvorogova V.E., Osipova M.A., Dodueva I.E., Lutova L.A.

Abstract

Plant growth and development are controlled by large regulatory network which modulates activity of special groups of cells — apical meristems. This control is performed by means of phytohormones and transcriptional factors, the regulators of gene expression. In this review principal transcriptional factors regulating plant apical meristems are described, and the data are presented about their interactions with the most important plant hormones, auxins, cytokinins and gibberellins. General tendencies of these interactions are depicted.
Ecological genetics. 2012;10(3):28-40
pages 28-40 views

Genotoxicology of plant compounds

Durnev A.D., Lapitskaya A.S.

Abstract

Experimental data obtained during genotoxicity investigation of herbal compounds were summarized. Compounds with established and/or presumed genotoxic activity were singled out. They include allyl isothiocyanates, anthraquinones, aristolochic acids, hydra-zines, propenyl benzenes, pyrrolizidine alkaloids, single flavonoids, etc. The data were analyzed critically and it was concluded that most of the results require confirmation, as they were obtained using inadequate test systems. Relevant trends and investigation algorithms used in genotoxicology studies of herbal compounds were defined.
Ecological genetics. 2012;10(3):41-52
pages 41-52 views

Comutagenic effects of valocordin

Durnev A.D., Daugel-Dauge N.O., Zhanataev A.K., Lapitskaya A.S., Seredenin S.B.

Abstract

The chromosome aberration test in bone marrow cells of mice was used to study the influence of valocordin on spontaneous and induced clastogenesis. Valocordin showed no inherent clastogenic activity. In experiments with pretreatment and with single or repeated combined administration , valocordin in doses of 0.03, 0.3 and 3 ml/kg significantly (47–133 %) enhanced the clastogenic activity of cyclophosphamide. There was no effect of valocordin on the cytogenetic activity of dioxidine, a mutagen with a pro-oxidative mode of action. Possible mechanisms of comutagenic activity of valocordin are discussed.
Ecological genetics. 2012;10(3):53-58
pages 53-58 views

The role of histone modifications and DNA methylation in renal cell carcinoma development

Kutlyeva L.R., Gilayzova I.R., Khusainova R.I., Khusnutdinova E.K.

Abstract

Epigenetic mechanisms of gene regulation play a key role in carcinogenesis. This review will focus on the recent advances of epigenetic investigations in the development of human cancer. The role of histone modifications, genomic imprinting and DNA methylation in renal cell carcinoma development and progression will be considered.
Ecological genetics. 2012;10(3):59-76
pages 59-76 views

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