Clinical and epidemiological features of the «dry eye» syndrome in patients with diabetes mellitus

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Abstract

The clinical and epidemiological features of the «dry eye» syndrome in patients with diabetes mellitus were studied. According to the data of visits to the outpatient department, the prevalence of this syndrome among patients with diabetes mellitus was 58.2±5.3%, among patients with an ophthalmological profile – 43.7±3.8% (p≤0.05). All patients were diagnosed with corneal-conjunctival xerosis of varying severity as: muco-filamentous discharge in the lower conjunctival fornix (in 61.1% of patients), reduction/absence of the meniscus at the edges of the eyelids (53.7%), local edema of the bulbar conjunctiva (35.8%), roughness and dullness of the cornea (30.5%). Significant discrepancies were found in the rates of tear production disorders depending on the severity of the clinical course of diabetes mellitus (p≤0.05), because of which diabetes mellitus can be considered as a aggravating factor for corneal-conjunctival xerosis.

About the authors

Z. A. Tajieva

Branch of 52 Consultative and Diagnostic Center of the Ministry of Defense of the Russian Federation

Author for correspondence.
Email: zim321@mail.ru

кандидат медицинских наук

Russian Federation, Moscow

O. I. Moloshkina

Branch of 52 Consultative and Diagnostic Center of the Ministry of Defense of the Russian Federation

Email: zim321@mail.ru
Russian Federation, Moscow

References

  1. Бржеский В.В., Астахов Ю.С., Кузнецова Н.Ю. Заболевания слезного аппарата: Пособие для практикующих врачей. – СПб: Изд-во Н-Л, 2009. – 108 с.
  2. Григорьева Н.Н., Пейч М.Е., Шадричев Ф.Е. Эффективность трегалозы в лечении синдрома «сухого глаза» у больных сахарным диабетом // Офтальмол. ведомости. – 2016. – Т. 9, № 2. – С. 19–26.
  3. Craig J. P., Nichols K.K., Akpek E.K. et al. TFOS DEWS II definition and classification report // Ocul. Surf. – 2017. – Vol. 15, N 3. – P. 276–283. doi: 10.1016/j.jtos.2017.05.008
  4. De Freitas G.R., Ferraz G.A.M., Gehlen M., Skare T.L. Dry eyes in patients with diabetes mellitus // Prim. Care Diabetes. – 2021. – Vol. 15, N 1. – P. 184–186. doi: 10.1016/j.pcd.2020.01.011
  5. Karki P., Sijapati M.J., Basnet P.S., Basnet A. Prevalence of dry eyes syndrome and retinopathy in diabetic patients and the association of glycosylated hemoglobin with retinopathy // J. Pathol. Nepal. – 2018. – Vol. 8, N 2. – P. 1369–1373. doi: 10.3126/jpn.v8i2.20887
  6. Kwak J.Y., Choi K.R., Han K.E., Jun R.M. Dry eye syndrome and morphological changes of meibomian glands in type 2 diabetic patients // J. Korean Ophthalmol. Soc. – 2019. – Vol. 60, N 11. – P. 1037–1042. doi: 10.3341/jkos.2019.60.11.1037
  7. Liu N.-N., Liu L., Li J., Sun Y.-Z. Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-Analysis // J. Ophthalmol. – 2014. – Vol. 2. – P. 1–8. doi: 10.1155/2014/748654
  8. Manaviat M.R., Rashidi M., Afkhami-Ardekani M., Shoja M.R. Prevalence of dry eye syndrome and diabetic retinopathy in type 2 diabetic patients // BMC Ophthalmol. – 2008. – Vol. 8, N 10. – P. 1–4. doi: 10.1186/1471-2415-8-10
  9. Saeedi P., Petersohn I., Salpea P. et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition // Diabetes Res. Clin. Prakt. – 2019. – Vol. 157. – P. 1–10. doi: 10.1016/j.diabres.2019.107843
  10. Seifart U., Strempel I. The dry eye and diabetes mellitus // Ophthalmologe. – 1994. – Vol. 91, N 2. – P. 235–239.
  11. Zhang X., Zhao L., Deng S. et al. Dry Eye Syndrome in Patients with Diabetes Mellitus: Prevalence, Etiology, and Clinical Characteristics // J. Ophthalmol. – 2016. – Vol. 2. – P. 1–7. doi: 10.1155/2016/8201053

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