Peripheral nerve injuries with extensive defects: experimental and topographic - anatomical approaches to substantiate accelerated tissue reinnervation

The article presents the results of a study in an experiment on laboratory animals’ peculiarities of muscle reinnervation and regeneration of a damaged peripheral nerve after its connection with an intact nerve in the «end - to - side» type. Evaluation of the results of restoration of tissue innervation after the link of the distal segment of the damaged nerve with the intact donor nerve, as well as the topographic and anatomical characteristics of the functionally significant branches of the peripheral nerves of the upper limb indicate the potential use of the peripheral nerve suture of the «end - to - side» type as one of the methods of tissue reinnervation for peripheral nerve injuries. In case of high proximal fractures, selective reinnervation of individual branches of the damaged nerve in the distal segments of the extremities will allow, in a shorter time, compared with the direct reconstruction of the nerve trunk at the level of injury, to restore the contractile activity of functionally essential muscle groups.

peripheral nerve, peripheral nerve injury, a peripheral nerve defect, nerve repair, end-to-side connection of peripheral nerves