Heat Capacity and Thermodynamic Properties of Mometasone Furoate

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Abstract

The temperature dependence of the heat capacity of mometasone furoate in the range from 6 to 500 K was determined by adiabatic vacuum calorimetry and differential scanning calorimetry for the first time. Standard thermodynamic functions of crystalline mometasone furoate were determined: heat capacity Cp°(T), enthalpy [H°(T) – H°(0)], enthalpy S°(T) Gibbs function [G°(T) – H°(0)] for the temperature range from T → 0 to 490 K. A regularity between the Debye temperature and the composition of steroid hormones was revealed.

About the authors

A. V. Knyazev

Lobachevsky National Research Nizhny Novgorod State University

Email: knyazevav@gmail.com
Nizhny Novgorod, Russia

N. N. Smirnova

Lobachevsky National Research Nizhny Novgorod State University

Nizhny Novgorod, Russia

O. V. Stepanova

Lobachevsky National Research Nizhny Novgorod State University

Nizhny Novgorod, Russia

S. S. Knyazeva

Lobachevsky National Research Nizhny Novgorod State University

Nizhny Novgorod, Russia

S. S. Sologubov

Lobachevsky National Research Nizhny Novgorod State University

Nizhny Novgorod, Russia

Yu. A. Sarmini

Lobachevsky National Research Nizhny Novgorod State University

Nizhny Novgorod, Russia

S. V. Chuprova

Lobachevsky National Research Nizhny Novgorod State University

Nizhny Novgorod, Russia

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