The importance of metabolic markers in the development of a second ischemic stroke
- Authors: Shishkova V.N1,2, Adasheva T.V2, Stakhovskaya L.V3
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Affiliations:
- Center for Speech Pathology and Neurorehabilitation, Moscow Healthcare Department
- A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
- N.I. Pirogov Russian National Research Medical University
- Issue: Vol 31, No 10 (2020)
- Pages: 65-68
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/114313
- DOI: https://doi.org/10.29296/25877305-2020-10-12
- ID: 114313
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Abstract
Objective. To investigate the relationship between plasma adiponectin (ADN) levels and the rate of a second noncardioembolic ischemic stroke (IS) over a three-year period Subjects and methods. The cohort observational study covered 206 patients who had experienced a first noncardioembolic IS, explored the clinical and metabolic parameters of the participants, and assessed the frequency and date of onset of a secondary IS using the Cutler-Ederer and Kaplan-Meier methods according to AND concentrations. Fasting plasma ADN concentrations (pg/ml) were determined using the BioVendor kits (Sweden) on a third-generation Reader UNIPLAN-9213 microplate photometer (PIKON, Russia). Results. The analysis of the frequency and date of onset of a second noncardioembolic IS over a three-year period showed an increased risk of its development in patients with low ADN levels (<7 pg/ml). Conclusion. The patients with a low ADN level are at a high risk for a second noncardioembolic IS.
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About the authors
V. N Shishkova
Center for Speech Pathology and Neurorehabilitation, Moscow Healthcare Department; A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Email: veronika-1306@mail.ru
T. V Adasheva
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
L. V Stakhovskaya
N.I. Pirogov Russian National Research Medical University
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