Clinical and morphological aspects of bladder cancer in elderly and senile ages

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Abstract

The clinical and morphological features of the course of bladder cancer (BC) were studied in 152 middle-aged, elderly, and senile male (86.9%) and female (13.1%) patients diagnosed with Stage I-IV BC: stage I in 116 (76.3%) patients and Stages II, III, IVin 36 (23.7%). Most patients underwent transurethral resection. Moderately differentiated bladder tumor was observed in 54.6% of patients. Microscopic examination of the tumor revealed an ordered histological and cellular structure with minor signs of nuclear atypia. Carcinomas consisted of cells with impaired polarity, which had lost intercellular contacts with large hyperchromatic nuclei. There were commonly mitotic figures, often atypical ones. There were no tumor histologic differences in different age groups (middle-aged, elderly and senile patients).

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About the authors

T. V. Pavlova

Belgorod State National Research University

Author for correspondence.
Email: pavlova@bsu.edu.ru

Professor

I. A. Pavlov

Belgorod State National Research University

Email: pavlova@bsu.edu.ru

Candidate of Biological Sciences

N. B. Pilkevich

Belgorod State National Research University

Email: pavlova@bsu.edu.ru

Professor

D. V. Bessmertnyi

Belgorod State National Research University

Email: pavlova@bsu.edu.ru

Candidate of Biological Sciences

V. A. Markovskaya

Belgorod State National Research University

Email: pavlova@bsu.edu.ru

Candidate of Biological Sciences

References

  1. Новиков А.И., Леоненков Р.В., Темкин Д.Б. и др. Трансуретральная резекция карциномы мочевого пузыря, распространяющейся на устье мочеточника. Онкоурология. 2021; 17 (2): 104-11. doi: 10.17650/1726-9776-2021-17-2-104-111
  2. Цеденова К.О., Комаров М.И., Панахов А.Д. и др. Мелкоклеточный рак мочевого пузыря: обзор литературы. Онкоурология. 2018; 14 (4): 103-9. doi: 10.17650/1726-97762018-14-4-103-109
  3. Состояние онкологической помощи населению России в 2020 г. Под ред. А.Д. Каприна, В.В. Старинского, А.О. Шахзадовой. М.: МНИОИ им. П.А. Герцена - филиал ФГБУ «НМИЦ радиологии» Минздрава России. 2021; 239.
  4. Коган М.И. Рак мочевого пузыря (классика и новации). М.: Медконгресс. 2019; 288.
  5. Белякова Л.И., Шевченко А.Н., Сагакянц А.Б. и др. Маркеры рака мочевого пузыря: их роль и прогностическая значимость (обзор литературы). Онкоурология. 2021; 17 (2): 145-56. doi: 10.17650/1726-9776-2021-17-2-145-156
  6. Карякин О.Б. Рак мочевого пузыря: что нового в 2019-2020 гг. Онкоурология. 2020; 16 (4): 147-54. doi: 10.17650/1726-9776-2020-16-4-147-154
  7. Онкогеронтология. Руководство для врачей. Под ред. В.Н. Анисимова, А.М. Беляева. СПб: Издательство АННМО «Вопросы онкологии», 2017; 509.
  8. Павлова Т.В., Пилькевич Н.Б., Бессмертный Д.В. и др. Особенности метаболического атипизма при развитии онкологической патологии мочеполовой системы. Молекулярная медицина. 2021; 19 (31): 30-4. doi: 10.29296/24999490-2021-01-04

Supplementary files

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2. Transitional cell BC (a male aged 55 years); the tissue consists of cells with im-paired polarity, which have lost intercellular contacts with large hyperchromatic nuclei; there are commonly mitotic figures, often atypical; magnification: а – ×250; б – ×100; в – ×100; г – ×400; H&E.

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