THERAPEUTICALLY RESISTANT ASTHMA


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Abstract

Therapy resistant asthma (TRA) is most difficult to treat and its course is least predictable. TRA remains least studied notwithstanding the fact that its many mechanisms have been detected. To this point there has been no clear definition of TRA and this terminology has not been widely used so far. This paper gives the results of an investigation, which could identify the phenotype of TRA, by taking into account its pathogenetic and clinical heterogeneity, reveal the predictors of the disease, and elaborate unique criteria to make its diagnosis.

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About the authors

V. Trofimov

Acad. I.P. Pavlov Saint Petersburg State Medical University

Email: trofvi@mail.ru

Zh. Mironova

Acad. I.P. Pavlov Saint Petersburg State Medical University

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