CLINICAL EFFICACY AND SAFETY OF BENF0LIPEN IN D0RS0PATHIES


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Abstract

The paper reports the results of complex therapy in patients with dorsopathy accompanied by pain and myotonic syndrome. It elevates the clinical efficacy of the Russian multivitamin complex Benfolipen that contains benfotiamine, of treatment for acute coronary syndrome with a fat-soluble analogue of thiamine.

About the authors

V Kukes

E Shikh

Email: chih@mail.ru

A Makhova

V Kukes

I.M. Sechenov Moscow Medical Academy

; I.M. Sechenov Moscow Medical Academy

E Shikh

I.M. Sechenov Moscow Medical Academy

; I.M. Sechenov Moscow Medical Academy

A Makhova

I.M. Sechenov Moscow Medical Academy

I.M. Sechenov Moscow Medical Academy

References

  1. Болезни нервной системы. Руководство для врачей. Под ред. Н.Н. Яхно, Д.Р. Штульмана. - М., 2001. - Т. 1.
  2. Данилов А.Б. Применение витаминов группы В при болях в спине: новые анальгетики?//РМЖ. -2008. - Спец. выпуск. - С. 35-39.
  3. Клинические рекомендации для практических врачей, основанные на доказательной медицине. - Издательский дом ГЭОТАР-МЕД. - 2001. -С. 606-611.
  4. Пентюк А. А. Модификация фармакокинетики ортофена и его аналь-гетической активности индукторами и ингибиторами активности ферментов метаболизма ксенобиотиков и тиаминдифосфатом // Фармакология и токсикология. - 1989; 52 (4): 61-64.
  5. Станиславчук Н.А. Оптимизация фармакотерапии ортофеном больных ревматоидным артритом //Дис. канд. мед. наук, 1991.
  6. Borenstein D. Эпидемиология, этиология, диагностическая оценка и лечение поясничной боли // Межд. мед. журн. - 2000; 35: 36-42.
  7. Bromm К., Herrmann W., Schulz H. Do the B-vitamins exhibit antinociceptive efficacy in men? Results of a placebo-controlled repeated-measures double-blind study // Neuropsychobiology. - 1995; 31(3): 156-165.
  8. Bruggemann G., Koehler C, Koch E. Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study // Klin Wochenschr. - 1990; 68(2):116-120.
  9. Franca D., Souza A., Almeida K. et al. В vitamins induce an antinociceptive effect in the acetic acid and formaldehyde models of nociception in mice // Eur. J. Pharmacol. - 2001; 421(3):157-164.
  10. Jurna I. Analgesic and analgesia-potentiating action of В vitamins// Schmerz. - 1998 Apr 20;12(2):136-41.
  11. Jurna I., Carlsson K., Komen W. et al. Acute effects of vitamin B6 and fixed combinations of vitamin B1, B6 and B12 on nociceptive activity evoked in the rat thalamus: dose-response relationship and combinations with morphine and paracetamol // Klin Wochenschr. - 1990; 68(2): 129-135.
  12. Kuhlwein A., Meyer H., Koehler С Reduced diclofenac administration by В vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus В vitamins) in acute lumbar vertebral syndromes//Klin Wochenschr - 1990; 68(2): 107-115.
  13. Vetter G., Bruggemann G., Lettko M. et al. Shortening diclofenac therapy by В vitamins. Results of a randomized double-blind study, diclofenac 50 mg versus diclofenac 50 mg plus В vitamins, in painful spinal diseases with degenerative changes // Z. Rheumatol. - 1988; 47(5): 351-362.
  14. Volvert M., Seyen S., Piette M. Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives // BMC Pharmacol. -2008; 8:10.
  15. WHO. Department of noncomunicable disease menagement. Low back pain iniciative. - Geneve, 1999.

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