NEW POTENTIALITIES OF MEDICAL THERAPY FOR CHRONIC BACTERIAL SINUSITIS


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The efficiency of combination therapy (the simultaneous use of antibacterial drugs and topical glucocorticoids) for exacerbations of different forms of bacterial sinusitis was determined. The study enrolled 60 patients aged 18 to 69 years. When the exacerbation of bacterial inflammation in paranasal sinuses was arrested with the antibiotic (moxifoxacin) and topical steroid combination proposed by the authors, the efficiency of treatment remained high and accounted for 88.9% for polypous and purulent sinusitis and 83.3% for the pyohyperplastic process following 6 months. Its efficacy for polypous lesion remained as before and that for hyperplasia slightly decreased (to 72.2%) after a year.

Full Text

Restricted Access

About the authors

A. Turovsky

Moscow Scientific and Practical Center of Otorhinolaryngology

Email: an_tur@mail.ru
MD

O. Semklna

Moscow Scientific and Practical Center of Otorhinolaryngology

References

  1. Лопатин А.С. Материалы ежегодной традиционной осенней конференции украинского научного медицинского общества оториноларингологов «Лор-онкология и хирургия головы и шеи». 18-20 сентября 2005.
  2. Cohen R. The antibiotic treatment of acute otitis media and sinusitis in children // Diagn. Microbiol. Infect. Dis. - 1997; 27: 49-53.
  3. Gwaltney J.M. Acute community-acquired sinusitis // Clin. Infect. Dis. 1996; 23: 1209-23.
  4. Hampel B. Clinical needs in the millennium-rhinosinusitis - the role of moxifloxacin. Ed. Mandell L. / 1st Intern. Moxifloxacin Symp., Berlin, 1999. Springer-Verlag, 2000; 174-7.
  5. Klossek J., Arvis P. et al. Moxifloxacin versus trovafloxacin in the treatment of acute bacterial maxillary sinusitis: a multinational, double-blind, randomised study / 3rd Eur. Congr. Chemother., Madrid, 2000; Poster.
  6. Lund V., Gwaltney J., Baguero F. et al. Infectious rhinosinusitis in adults: classification, etiology and management // J. Ear. Nose Throat. - 1997; 76: 22.
  7. Lund V., Kennedy D. // Ann. Otol. Rhinol. Laringol. - 1995; 167 (Suppl. h): 17-21.
  8. Stierna P. In: Kennedy D., Bolger W., Zinreich S., eds. Diseases of the sinuses: diagnosis and management. Hamilton, Ontario: B.C. Decker / 2001; p. 35-46.
  9. Quintiliani R., Owens R., Grant E. Clinical role of fluoroquinolones in patients with respiratory tract infections // Infect. Dis. Clin. Pract. - 1999; 8 (Suppl. 1): 28-41.
  10. Brannan M., Seiberling V., Cutler D. et al. Lack of systemic activity with intranasal mometasone furoate // Ann. Allerg. Asthma Immunol. - 1997; 97: 198.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2012 Russkiy Vrach Publishing House

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies