THE EFFICIENCY, SAFETY, AND TOLERANCE OF ROSUVASTATIN THERAPY IN VERY HIGH CARDIOVASCULAR RISK PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA: PRELIMINARY RESULTS OF THE 40x40 STUDY


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Abstract

The main objective of the pilot 40 x 40 study was to evaluate the hypolipidemic efficacy, safety, and tolerance of the generic rosuvastatin Mertenil in a high daily dose of 40 mg/day in very high cardiovascular risk patients who failed to achieve low-density lipoprotein cholesterol goals during current statin therapy in daily clinical practice. The data of a follow-up during the first 12-week therapy are given.

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About the authors

M. Zubareva

Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development of Russia

Email: asus99@mail.ru
Candidate of Medical Sciences

T. Rozhkova

Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development of Russia

Email: asus99@mail.ru
Candidate of Medical Sciences

N. Gornyakova

Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development of Russia

Email: asus99@mail.ru
Candidate of Medical Sciences

E. Solovyeva

Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development of Russia

Email: asus99@mail.ru
Candidate of Medical Sciences

A. Susekov

Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development of Russia

Email: asus99@mail.ru
MD

V. Kukharchuk

Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development of Russia

Email: asus99@mail.ru
MD, Correspondent Member of the Russian Academy of Medical Sciences Laboratory of Clinical Lipidology, Department of Atherosclerosis Problems

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