RISK FACTORS FOR PRECANCER OF THE CERVIX UTERI


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Abstract

Examinations were made in 384 patients with cervical cancer (CIN I, CIN II, CIN III) in the presence of infection with human papillomavirus (HPV) and 84 patients without CIN and HPV. Comprehensive examination involved analysis of anamnestic data (the specific features of sexual behavior and used contraceptive methods, reproductive function), as well as colposcopy, cytological and histological studies of cervical biopsy specimens, polymerase chain reaction for HPV. Early onset of sexual intercourse, promiscuity, irregular barrier contraceptive use or its absence, an insignificant interval between menarche and onset of sexual activity were established to be social risk factors of CIN. Measures for primary prevention of CIN are presented.

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About the authors

T. Klinyshkova

Omsk State Medical University

Professor MD

T. Karatyuk

Omsk State Medical University

Email: tkaratuk@mail.ru
Candidate of Medical Sciences

D. Turchaninov

Omsk State Medical University

MD

References

  1. Голованова В.А., Новик В.И., Гуркин Ю.А. Частота и факторы риска папилломавирусной инфекции и дисплазии эпителия шейки матки у сексуально активных девушек-подростков // Вопр. онкол. - 1999; 45 (6): 623-6.
  2. Клинышкова Т.В., Каратюк Т.И., Турчанинов Д.В. и др. Дифференцированный подход к ведению больных с цервикальной интраэпителиальной неоплазией с позиции прогнозирования // Гинекология. - 2011; 13 (4): 39-44.
  3. Минкина Г.Н., Манухин И.Б., Франк Г.А. Предрак шейки матки - М.: Аэрограф-медиа, 2001; 118 с.
  4. Роговская С.И. Практическая кольпоскопия // М.: ГЭОТАР-Медиа, 2010.
  5. Caiyan X. Prevalence and risk factors of lower genital tract infections among women in Beijing, China // J. Obstet. Gynaecol. Res. - 2012; 38 (1): 1447-50.
  6. Collins S. Cigarette smoking is an independent risk factor for cervical intraepithelial neoplasia in young women: a longitudinal study. S. Collins et al. // Eur. J. Cancer. - 2010; 46 (2): 405-11.
  7. Duggan M.A. Predictors of co-incidental CIN II/III amongst a cohort of women with CIN I detected by a screening Pap test // Eur. J. Gynaecol. Oncol. -1998; 19 (3): 209-14.
  8. Frega A. Young women, cervical intraepithelial neoplasia and human papillomavirus: risk factors for persistence and recurrence // Cancer Lett. - 2003; 196 (2): 127-34.
  9. Kjellberg L. Smoking, diet, pregnancy and oral contraceptive use as risk factors for cervical intra-epithelial neoplasia in relation to human papillomavirus infection // Br. J. Cancer. - 2000; 82 (7): 1332-8.
  10. Nùnez J. Prostitution and other cofactors in preinvasive and invasive lesions of the cervix // Aust. N. Z. J. Obstet. Gynaecol.- 2004; 44 (3): 239-43.
  11. Stefänescu B. Adenocarcinoma of the uterine cervix--risk factors // Rev. Med. Chir. Soc. Med. Nat. Iasi. - 2007; 111 (1): 155--60.
  12. Syrjänen K. New concepts on risk factors of HPV and novel screening strategies for cervical cancer precursors // Eur. J. Gynaecol. Oncol. - 2008; 29 (3): 205-21.
  13. Tolstrup J. The role of smoking and alcohol intake in the development of high-grade squamous intraepithelial lesions among high-risk HPV-positive women // Acta Obstet. Gynecol. Scand. - 2006; 85 (9): 1114-9.
  14. Trottier H. Persistence of an incident human papillomavirus infection and timing of cervical lesions in previously unexposed young women // Cancer Epidemiol. Biomarkers. Prev. - 2009; 854 (62): 854-62.
  15. Zivadinovic R. Recurrence of cervical intraepithelial neoplasias with negative cone margins: risk factors // J. Buon. - 2011; 16 (3): 498-504.
  16. Zivaljevic B. Smoking as risk factor for cervical cancer // Neoplasma. -2001; 48 (4): 254-6.
  17. Human papillomaviruses in the pathogenesis of anogenital cancer // Virology. - 1991; 184 (1): 9-13.

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