PRIMARY AL AMYLOIDOSIS: NEW INSIGHTS INTO ITS PATHOGENESIS, DIAGNOSIS, AND TREATMENT


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Abstract

The rate of production of the amyloid precursor protein - free immunoglobulin light chains (FLC) - is an important factor for estimating disease prognosis and therapeutic effectiveness. A 3-fold FLC reduction as compared to the normal values has increased the chances of a good prognosis by about 6 times.

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About the authors

V. Rameev

I.M. Sechenov First Moscow State Medical University

Email: vvrameev@mtu-net.ru

L. Kozlovskaya

I.M. Sechenov First Moscow State Medical University

K. Gudkova

I.M. Sechenov First Moscow State Medical University

I. Kogarko

N.N. Semenov Institute of Chemical Physics, Russian Academy of Sciences

B. Kogarko

I.M. Sechenov First Moscow State Medical University; N.N. Semenov Institute of Chemical Physics, Russian Academy of Sciences

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