CURRENT UNDERSTANDING OF PATHOPHYSIOLOGICAL ASPECTS OF GERD AND APPROACHES TO PHARMACOTHERAPY


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Abstract

Heartburn is considered to be the main symptom of gastroesophageal reflux disease (GERD) which significantly affects the quality of patient life. The current studies showed that the most frequent cause of heartburn after eating was the accumulation of acid on the gastric contents surface - the formation of the socalled «acid pocket». Neutralizing the acid pocket is not an easy task even for antisecretory agents. And to prevent gastroesophageal reflux after eating is even a more complicated task. The modern and safe alginate - andantacid-based drug Gaviscon Double Action offers an effective solution to this problem by producing a double effect due to its antacid and antireflux properties.

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O. Yanova

Central Research Institute of Gastroenterology

Email: redvrach@rusvrach.ru

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