HEPATOCYTE DYSPLASIA IN HBeAg-NEGATIVE CHRONIC HEPATITIS B WITH DIFFERENT HBsAg PHENOTYPES OF VIRAL INFECTION


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Abstract

Examination of 58 patients with HBeAg-negative chronic hepatitis B (CHB) with HBsAg +- and HBsAg - phenotypes of hepatitis B virus infection revealed a considerable predominance of small liver cell dysplasia over large liver cell one, an upward trend for liver cell dysplasia in HBsAg loss, and a direct correlation of hepatocyte dysplasia with the magnitude of a necrotic/inflammatory process and the hepatocyte levels of HBcorAg in HBsAg -.

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About the authors

O. Dudanova

Petrozavodsk State University

Email: odudanova@gmail.com
MD

I. Pravdolyubova

Petrozavodsk State University

Candidate of Medical Sciences

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