SIMULATION OF GASTROESOPHAGEAL REFLUX DISEASE IN OLD AGE GROUPS


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

A 5-year prospective cohort study was conducted in patients (mean age 69.0±5.9 years) with gastroesophageal reflux disease. The results of discriminant analysis were used to derive original formulas that are supported by a Russian Federation patent for invention and can predict the unfavorable course of the disease in elderly patients to an accuracy of 97.1%.

Full Text

Restricted Access

About the authors

E. Onuchina

Irkutsk State Medical University

Email: elonu@mail.ru

V. Tsukanov

Research Institute of Medical Problems of the North, Siberian Branch, Russian Academy of Medical Sciences

N. Kozlova

Irkutsk Diagnostic Center

References

  1. Azumi T., Adachi K., Arima N. et al. Five-year follow-up study of patients with reflux symptoms and reflux esophagitis in annual medical check-up field // Intern. Med. - 2008; 47 (8): 691-6.
  2. Hershcovici T., Fass R. Nonerosive Reflux Disease (NERD) - An Update //J. Neurogastroenterol. Motil. - 2010; 16: 8-21.
  3. Lundell L., Dent J., Bennet J. Endoscopic assessment of oesophagitis clinical and fuctional correlates and futher validation of Los Angeles classification // Gut. - 1999; 45: 72-180.
  4. Malfertheiner P., Nocon M., Vieth M. et al. Evolution of gastro-oesophageal reflux disease over 5 years under routine medical care - the ProGERD study // Aliment. Pharmacol. Ther. - 2012; 35 (1): 154-64.
  5. Miyamoto M., Haruma K., Kuwabara M. et al. Long-term gastroesophageal reflux disease therapy improves reflux symptoms in elderly patients: five-year prospective study in community medicine // J. Gastroenterol. Hepatol. - 2007; 22 (5): 639-44.
  6. Pilotto A., Leandro G., Franceschi M. Ageing and Acid-Related Disease Study Group.Short- and long-term therapy for reflux oesophagitis in the elderly: a multicentre, placebo-controlled study with pantoprazole // Aliment. Pharmacol. Ther. -2003; 17 (11): 1399-406.
  7. Spechler S., Sharma P., Souza R. et al. American Gastroenterological Association technical review on the management of Barrett's esophagus // Gastroenterology. - 2011; 140 (3): 18-52.
  8. Stoltey J., Reeba H., Ullah N. et al. Does Barrett's oesophagus develop over time in patients with chronic gastro-oesophageal reflux disease? // Aliment. Pharmacol. Ther. - 2007; 25 (1): 83-91.
  9. Vakil N., van Zanten S., Kahrilas P. et al. The Monreal Definition and Classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterology. - 2006; 101: 1900-20.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies