RISK OF LONG-TERM USE OF LAXATIVES


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Abstract

The paper presents the pathogenetic and clinical aspects associated with the irrational and long-term use of laxatives and discusses diagnostic and therapeutic approaches to managing patients with clinical manifestive types of laxative abuse.

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About the authors

I. Mayev

A.I. Evdokimov Moscow State University of Medicine and Dentistry

Email: dna-mit8@mail.ru
Correspondent Member of the Russian Academy of Medical Sciences

D. Andreev

A.I. Evdokimov Moscow State University of Medicine and Dentistry

Email: dna-mit8@mail.ru

D. Dicheva

A.I. Evdokimov Moscow State University of Medicine and Dentistry

Email: dna-mit8@mail.ru
Candidate of Medical Sciences

I. Gurtovenko

I.M. Sechenov First Moscow State Medical University

Email: dna-mit8@mail.ru
Candidate of Medical Sciences

References

  1. Roerig J., Steffen K., Mitchell J. et al. Laxative abuse: epidemiology, diagnosis and management // Drugs. - 2010; 70 (12): 1487-503.
  2. Гастроэнтерология. Национальное руководство (краткое изд.). Под ред. В.Т. Ивашкина, Т.Л. Лапиной / М.: ГЭОТАР-Медиа, 2011; 480 c.
  3. Маев И.В., Самсонов А.А., Дичева Д.Т. и др. Обстипационный синдром // Мед. вестн. МВД. - 2012; 59 (4): 42-5.
  4. Morales M., Hernandez D., Bustamante S. et al. Is senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity? // J. Toxicol. - 2009; 2009: 287247.
  5. Hallmann F. Toxicity of commonly used laxatives // Med. Sci. Monit. - 2000; 6 (3): 618-28.
  6. Tozzi F., Thornton L., Mitchell J. et al. Features associated with laxative abuse in individuals with eating disorders // Psychosom. Med. - 2006; 68: 470-7.
  7. Vanin J., Saylor K. Laxative abuse: a hazardous habit for weight control // J. Am. Coll. Health. - 1989; 37: 227-30.
  8. Pomeroy C., Mitchell J., Roerig J. et al. Medical complications of psychiatric illness / Washington, DC: American Psychiatric Publishing Inc., 2002; 35-74.
  9. Baker E., Sandle G. Complications of laxative abuse // Ann. Rev. Med. -1996; 47: 127-34.
  10. Marquart L., Sobal J. Weight loss beliefs, practices and support systems for high school wrestlers // J. Adolesc. Health. - 1994; 15: 410-5.
  11. Shelton J., Santa-Ana C., Thompson D. et al. Factitious diarrhea induced by stimulant laxatives: accuracy of diagnosis by a clinical reference laboratory using thin layer chromatography // Clin. Chem. - 2007; 53: 85-90.
  12. Keswani R., Sauk J., Kane S. Factitious diarrhea masquerading as refractory celiac disease // South Med. J. - 2006; 99: 293-5.
  13. Savino A., Fordtran J. Factitious disease: Clinical lessons from case studies at Baylor University Medical Center // Proc. Bayl. Univ. Med. Cent. - 2006; 19: 195-208.
  14. Phillips S. Surreptitious laxative abuse: Keep it in mind // Semin. Gastrointest. Dis. - 1999; 10: 132-7.
  15. Neims D., McNeill J., Giles T. et al. Incidence of laxative abuse in community and bulimic populations: a descriptive review // Int. J. Eat. Disord. - 1995; 17: 211-28.
  16. Steffen K., Mitchell J., Roerig J. The eating disorders medicine cabinet revisited: a clinician's guide to ipecac and laxatives // Int. J. Eat. Disord. - 2007; 40: 360-8.
  17. Creytens G. Le Lactulose dans le traitement de la constipation chronique et labus des laxatives // Ars médici. - 1980; 35: 737-57.
  18. Kokot F., Hyla-Klekot L. Drug-induced abnormalities of potassium metabolism // Pol. Arch. Med. Wewn. - 2008; 118 (7-8): 431-4.
  19. Wald A. Is chronic use of stimulant laxatives harmful to the colon? // J. Clin. Gastroenterol. - 2003; 36: 386-9.
  20. Wright L., DuVal J. Renal injury associated with laxative abuse // South Med. J. - 1987; 80: 1304-6.
  21. Vanderperren B., Rizzo M., Angenot L. et al. Acute liver failure with renal impairment related to the abuse of senna anthraquinone glycosides // Ann. Pharmacother. - 2005; 39: 1353-7.
  22. Минушкин О.Н. Осложнения фармакотерапии хронического запора // РМЖ. - 2003; 5 (3): 52-5.
  23. Slugg P., Carey W. Clinical features and follow-up of surreptitious laxative users // Cleveland Clin. Q. - 1984; 51: 167-71.
  24. Urso F., Urso M., Lee C. The cathartic colon: pathological findings and radiological/pathological correlation // Radiology. - 1975; 116 (3): 557-9.
  25. Campbell W. Cathartic colon. Reversibility of roentgen changes // Dis. Colon. Rectum. - 1983; 26 (7): 445-8.
  26. Freeman H. «Melanosis» in the small and large intestine // W. J. Gastroenterol. - 2008; 14 (27): 4296-9.
  27. Kostela E., Kulju T., Collan Y. Melanosis coli, prevalence, distribution and histological features in 200 consecutive autopsies at Kuopio University Central Hospital // Dis. Colon. Rectum. - 1989; 32 (3): 235-9.
  28. Ahasan H., Khan A., Mahbub H. et al. Melanosis Coli - An Atypical Presentation // J. Med. - 2010; 11 (2): 183-5.
  29. Walker N., Bennett R., Axelsen R. Melanosis coli. A consequence of anthraquinone induced apoptosis of colonic epithelial cells // Am. J. Pathol. - 1988; 131 (3): 465-6.
  30. Müller-Lissner S. The pathophysiology, diagnosis, and treatment of constipation // Deutsch. Arztebl. Int. - 2009; 106 (25): 424-31.
  31. Harris A., Buchanan G. Melanosis coli is reversible // Colorectal. Dis. -2009; 11: 788-9.
  32. Greenfeld D., Mickley D., Quinlan D. et al. Hypokalemia in outpatients with eating disorders // Am. J. Psychiatry. - 1995; 152: 60-3.
  33. Duncan A. Screening for surreptitious laxative abuse // Ann. Clin. Biochem. -2000; 37: 1-8.
  34. Phillips S., Donaldson L., Geisler K. et al. Stool composition in factitial diarrhea: a 6-year experience with stool analysis // Ann. Intern. Med. - 1995; 123 (2): 97-100.
  35. Маев И., Дичева Д., Андреев Д. Новые возможности лечения хронического запора // Врач. - 2012; 3: 45-8.
  36. Wanitschke R., Goerg K., Loew D. Differential therapy of constipation -a review // Int. J. Clin. Pharmacol. Ther. - 2003; 41 (1): 14-21.
  37. Маев И.В., Самсонов А.А., Андреев Д.Н. Современный алгоритм ведения пациентов с синдромом хронического запора с позиций внедрения новых фармакологических препаратов // Фарматека. - 2012; 13: 37-43.
  38. Черемушкин С., Кучерявый Ю. Доказательная медицина и лечение хронического запора // Врач. - 2012; 10: 42-7.
  39. Marlett J., Kajs T., Fischer M. An unfermented gel component of psyllium seed husk promotes laxation as a lubricant in humans // Am. J. Clin. Nutr. - 2000; 72: 784-9.
  40. Mehmood M., Aziz N., Ghayur M. et al. Pharmacological basis for the medicinal use of psyllium husk (Ispaghula) in constipation and diarrhea // Dig. Dis. Sci. - 2011; 56 (5): 1460-71.
  41. Hotz, J., Plein, K. Wirkung von Plantago-Samenschalen im Vergleich zu Weizenkleie auf Stuhlfrequenz und Beschwerden beim Colonirritabile Syndrom mit Obstipation // Med. Klin. - 1994; 89: 645-51.
  42. Dettmar P., Sykes J. A multi-centre, general practice comparison of ispaghula husk with lactulose and other laxatives in the treatment of simple constipation // Curr. Med. Res. Opin. - 1998; 14 (4): 227-33.

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