PROGRESSIVE GASTROESOPHAGEAL REFLUX DISEASE IN ELDERLY PEOPLE AND RISK FACTORS
- Authors: Onuchina E.1, Tsukanov V.2, Kozlova N.3
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Affiliations:
- Irkutsk State Medical Academy for Postgraduate and Continuing Education
- Research Institute of Medical Problems of the North, Siberian Branch, Russian Academy of Medical Sciences
- Ikutsk Diagnostic Center
- Issue: Vol 25, No 1 (2014)
- Pages: 69-71
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/115959
- ID: 115959
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Abstract
During a 5-year follow-up of elderly patients, the likelihood of transformation of nonerosive reflux disease (NERD) to erosive reflux disease (ERD) or Barretts esophagus (BE) was 46,4 and 2,5%, respectively. ERD was a stable form in 66,8% of the patients, it transformed to NERD or BE in 26,0 and 6,4%, respectively. Lower third esophageal dysplasia occurred in 8,1% of the patients with BE during the follow-up. In the elderly patients, the leading risk factors of progressive gastroesophageal reflux disease were the absence of maintenance therapy with proton pump inhibitors (odds ratio (OR) = 6,2%; confidence interval (CI), 1,8-8,8), abdominal obesity (OR 3,1; CI, 2,3-3,9), tobacco smoking (OR 2,3; CI, 1,5-3,1); regular alcohol use (OR, 2,0; CI, 1,1-2,7).
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About the authors
E. Onuchina
Irkutsk State Medical Academy for Postgraduate and Continuing Education
Email: elonu@mail.ru
MD
V. Tsukanov
Research Institute of Medical Problems of the North, Siberian Branch, Russian Academy of Medical Sciences
Email: elonu@mail.ru
Professor, MD
N. Kozlova
Ikutsk Diagnostic Center
Email: elonu@mail.ru
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