ROLE OF OXIDATIVE STRESS IN THE PATHOGENESIS OF NEONATAL MULTIPLE ORGAN DYSFUNCTION
- Authors: Serebryakova E.1, Minochkin P.1, Volosnikov D.1
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Affiliations:
- South Ural State Medical University
- Issue: Vol 25, No 2 (2014)
- Pages: 64-66
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/115961
- ID: 115961
Cite item
Abstract
Multiple organ dysfunction (MOD) is one of the most pressing problems of neonatology. This investigation has shown that the condition of newborn infants with MOD is determined by the intensity of oxidative stress. The topical areas of neonatology are to search and design of drugs with antioxidant properties and to study their efficacy.
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About the authors
E. Serebryakova
South Ural State Medical University
Email: doctor-hit@yandex.ru
Candidate of Medical Sciences Chelyabinsk
P. Minochkin
South Ural State Medical University
Email: doctor-hit@yandex.ru
Candidate of Medical Sciences Chelyabinsk
D. Volosnikov
South Ural State Medical University
Email: doctor-hit@yandex.ru
Candidate of Medical Sciences; Professor Chelyabinsk
References
- Александрович Ю.С., Нурмагамбетова Б.К., Пшениснов К.В. и др. Особенности течения синдрома полиорганной недостаточности у доношенных и недоношенных новорожденных // Вопр. практ. педиатрии. - 2009; 4 (1): 14-6.
- Волчегорский И.А., Налимов А.Г., Яровинский Б.Г. и др. Сопоствление различных продуктов перекисного окисления липидов в гептанизопропанольных экстрактах // Вопр. мед. химии. - 1989; 1: 127-31.
- Герасимов Л.В., Мороз В.В., Исакова А.А. Микрореологические нарушения при критических состояниях // Общая реаниматология. - 2010; 6 (1): 74-8.
- Лисовский В.А., Гущ В.Н., Кидалов В.Н. Трансформация эритроцитов как диагностический тест в клинической практике // Лаб. дело. - 1986; 10: 594-8.
- Орлов Ю.П. Внутрисосудистый гемолиз эритроцитов в развитии органных дисфункций при критических состояниях // Общая реаниматология. - 2008; 4 (2): 88-93.
- Bestati N., Leteurtre S., Duhamel A. et al. Differences in organ dysfunctions between neonates and older children: a prospective, observational, multicenter study // Crit. Care. - 2010; 14 (6): 202.
- Janota J., Simak J., Stranak Z. et al. Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU // Ir. J. Med. Sci. - 2008; 177 (1): 11-7.
- Nassi N., Ponziani V., Becatti M. et al. Anti-oxidant enzymes and related elements in term and preterm newborns // Pediatr. Int. - 2009; 51 (2): 183-7.
- Tsuda K. Oxidative stress and membrane fluidity of red blood cells in hypertensive and normotensive men: an electron spin resonance investigation // Int. Heart J. - 2010; 51 (2): 121-4.
- Vileno B., Jeney S., Sienkiewicz A. et al. Evidence of lipid peroxidation and protein phosphorylation in cells upon oxidative stress photo-generated by fullerols // Biophys. Chem. - 2010; 152 (1-3): 164-9.