THREE-DIMENSIONAL BIO-PRINTING OF ORGANS: ETHICAL AND LEGISLATIVE ASPECTS


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Abstract

3D (three-dimensional) bio-printing is a promising alternative to donation, which must solve the problem of donor organ shortage. However, there are a number of ethical and legislative problems that should be solved by the time that the first transplantation-suitable organs (3D constructions) are designed and the first transplantations done.

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About the authors

A. Melerzanov

Moscow Institute of Physics and Technology

Email: m83071@gmail.com
Candidate of Medical Sciences

A. Mishra

Moscow Institute of Physics and Technology

N. Manturova

N.I. Pirogov Russian National Research Medical University

MD Moscow

References

  1. www.garant.ru
  2. The Need Is Real: Data, U.S. Dep’t Health&Hum. Services, http://www. organdonor.gov/about/data.html
  3. Готье С.В., Мойсюк Я.Г., Хомяков С.М. Донорство и трансплантация органов в РФ в 2014 VII сообщение регистра Российского трансплантологического общества // Вестник трансплантол. и искусственных органов. - 2015; 17 (2): 7-22.
  4. Varkey M., Atala A. Organ Bioprinting:A closer look at Ethicsand policies / Winston-Salem, North Carolina, USA: Wake Forest Institute for Regenerative Medicine.
  5. Consolidated versions of the Treaty on European Union and the Treaty on the Functioning of the European Union and the Charter of Fundamental Rights of the European Union. http://data.consilium.europa.eu/doc/document/ST-6655-2008-REV-8/en/pdf
  6. Organ transplantation legal aspects: http://www.drze.de/
  7. Communication from the commission: http://ec.europa.eu/health
  8. Macchiarini P. Bioartificial tracheobronchial transplantation. Interview with Paolo Macchiarini // Regen Med. - 2011; 6 (6 Suppl.): 14-5.
  9. De Filippo R., Kornitzer B., Yoo J. et al. Penile urethra replacement with autologous cell-seeded tubularized collagen matrices // J. Tissue Eng. Regen Med. - 2015; 9 (3): 257-64.
  10. Atala A. et al. Engineering Complex Tissues, 4 SCI // Translational Med. -2012; 160 (2): www.stn.scicncemag.org/contentM/ 160/160rv 12.
  11. D Bioprinting Solutions Succeeds in Performing the First 3D Printed Thyroid Transplant by Clare Scott. Nov 4, 2015. 3D Printing, Health 3D Printing.
  12. First 3D Printed Titanium Jaw Implant Successful, Brooke Kaclin, 3D Printer World (Aug. 16, 2013). http://www.3dprinterworld.com/article/first-3d-printcd-titaniu In-jaw-implant-successful
  13. The Future of Prosthetics: 3D Printed Nose, Ear and Eye, 3DERS (Nov. 8, 2013), http://www.3ders.org/articles/20131108-the-fiuture-of-prosthetics3d-printed-nose-car-and-cye.html (describing the printing of ears, noses, and eyes).
  14. Nair K. et al. Characterization of Cell Viability During Bioprinting Processes // Biotech. J. - 2009; 1168: 1174-5.
  15. Michael S. et al. Tissue Engineered Skin Substitutes Created by Laser-Assisted Bioprinting Form Skin-Like Structures in the Dorsal Skin Fold Chamber in mice // PLoS One. - 2013; 8 (3): e57741.
  16. Mironov V. et al. Organ Printing: Tissue Spheroids as Building Blocks // Bioprinting. - 2009; 30 (12): 2164-74.
  17. Zaher W. et al. An Update of Human Mesenchymal Stem Cell Biology and Their Clinical Use // Arch. Toxicol. - 2014; 88: 1069-76.
  18. Проект ФЗ «О биомедицинских клеточных продуктах» http://www. rosminzdrav.ru/
  19. Chirba M., Noble A. Our Bodies, Our Cells: FDA Regulation of Autologous Adult Stem Cell Therapies. Bill of Health Petrie-Flom Center http://blogs.harvard. edu/
  20. Richard E. Body Parts, Property rights and the ownership of Human biological materials // J. Law Technol. - 1997; 10 (2): 240.
  21. Мелерзанов А., Мантурова Н. Минимально манипулированный клеточный продукт в пластической хирургии и регенеративной медицине // Врач. -2015; 8: 78-80.
  22. Зиновьева Н.А., Мелерзанов А.В., Петерсен Е.В. и др. Использование трансгенных GAL-KO свиней в ксенотрансплантации: проблемы и перспективы // Сельскохозяйственная биология. - 2014; 2: 42-9.
  23. Thasler W. et al. Charitable State-Controlled Foundation Human Tissue and Cell Research: Ethic and Legal Aspects in the Supply of Surgically Removed Human Tissue for Research in the Academic and Commercial Sector in Germany // Cell Tissue bank. - 2003; 49: 51.
  24. Williams Faulkner G. et al. Patenting of Stem Cells // Regenerative Med. -2006; 80: 697.
  25. Association for Molecular Pathology v. Myriad Genetics, Inc., 113 S. Ct. 2107 (2013).
  26. Kapp M. Ethical and Legal Issues in Research Involving Human Subjects: Do You Want a Piece of Me? // J. Clin. Pathol. - 2006; 59: 335-7.

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