Vol 27, No 5 (2016)

Current studies can detect pulmonary focal masses of the smallest diameter. At the same time, great problems arise in their differential diagnosis. Removal of pathological pulmonary focal masses of small size (0.5 to 2 cm) is indicated in all patients who are found to have the latter without preoperative morphological verification of the diagnosis.

3D (three-dimensional) bio-printing is a promising alternative to donation, which must solve the problem of donor organ shortage. However, there are a number of ethical and legislative problems that should be solved by the time that the first transplantation-suitable organs (3D constructions) are designed and the first transplantations done.

Clinical and immunological examinations were made in 95 reproductive-aged women with inflammatory diseases of the urinary system, the etiological agents of which were Mycoplasma genitalium and herpes simplex virus 1 and 2. The found imbalance of clinical parameters and defects in innate adaptive immunity and levels of the cytokines interleukin (IL)-1, IL2, tumor necrosis factor, and interferon-y in the cervical secretion was successfully corrected by incorporating Roncoleukin® 500,000 U diluted in 5.0 ml of saline and injected on a gynecological tampon for 2 hours every 10 days into a package of therapeutic measures during mainstay therapy.

The paper provides evidence for the high efficiency and relative safety of plasmapheresis in the complex of preparation in patients with anti-HLA antibodies for kidney transplantation and their postoperative management.

Examination of patients with chronic kidney disease who were treated with peritoneal dialysis in standard and adapted modes showed that the latter mode enabled the patients to have more freedom in the daytime without worsening homeostatic parameters.

The paper gives the results of studying the specific features of the clinical picture and the data of additional studies of mesenteric panniculitis (MPN) as one of the types of Weber-Christian panniculitis. It demonstrates that it is necessary to thoroughly examine patients with panniculitis in order to verify the diagnosis of MPN and emphasizes the significance of the examination for practitioners of various specialties.

Positive changes have been found in the activity of psoriatic arthropathy (PA) caused by the molecular components of the mechanism of action of Osteomed Forte during basic therapy. The drug is promising in treating and preventing PA and well tolerated.

Individual drug sensitivity that is largely determined by the polymorphism of genes encoding the enzymes metabolizing this drug remains one of the main causes of the high incidence of poor outcomes of pregnancy.

The performed analysis has confirmed the efficiency of PlasmoliftingTM in treating shoulder joint injury, including adhesive capsulitis, and the need for further investigations of the above technique used for chronic sports injuries.

Owing to the wide use of radiodiagnostic techniques, clinicians increasingly frequently encounter isolated splenomegaly, one of the causes of which may be lymphoproliferative diseases (LPDs). The enlarged spleen in LPDs may be both primary and secondary to disseminated tumors at other sites. The term splenic lymphoma (SL) is discussed in detail; LPDs that may be considered as SL. The application of an examination algorithm is one of the important components of the diagnosis of SL. A diagnostic algorithm is given with an indication of current studies.

Analysis of the 1945-2015 enactments of the Ministry of Health of Russia could reveal a trend in the formation and development of a service, as well as methods for the early diagnosis of benign and malignant breast tumors; shortages of its organization were revealed.

The author shares memories of his work at a frontline hospital during Moscow defense in 1941-1942.