FIBROGENESIS AS AN OBJECT OF PHARMACOLOGICAL REGULATION: ALTERNATIVE ABILITIES OF SLOW-RELEASE CALCIUM CHANNEL BLOCKERS


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅或者付费存取

详细

The paper discusses whether slow-release calcium channel blockers (SCCBs) may be used to regulate the processes of connective tissue formation. The main pathogenetic components of fibrogenesis, which determine the expediency of the administration and efficiency of SCCBs, are defined. The authors give the results of their own studies of the antifibrotic effect of verapamil.

全文:

受限制的访问

作者简介

S. Skalsky

Omsk State Medical University

Email: sergscalskiy@mail.ru
Candidate of Medical Sciences

D. Sychev

Russian Medical Academy of Postgraduate Education

Professor

参考

  1. Wynn T., Ramalingam T. Mechanisms of fibrosis: therapeutic translation for fibrotic disease // Nat. Med. - 2012; 18 (7): 1028-40.
  2. Speca S., Giusti I., Rieder F. et al. Cellular and molecular mechanisms of intestinal fibrosis // WJG. - 2012; 18 (28): 3635-61.
  3. Hinz B., Phan S., Thannickal V. et al. Recent Developments in Myofibroblast Biology: Paradigms for Connective Tissue Remodeling // Am. J. Pathol. - 2012; 180 (4): 1340-55.
  4. Janssen L., Mukherjee S., Ask K. Calcium Homeostasis and Ionic Mechanisms in Pulmonary Fibroblasts // Am. J. Respir. Cell Mol. Biol. (Online). - 2015; 53 (2): 135.
  5. Prakriya M., Lewis R. Store-operated calcium channels // Physiol. Rev. -2015; 95 (4): 1383-436.
  6. Ben-Johny M., Yue D. Calmodulin regulation (calmodulation) of voltage-gated calcium channels // J. Gen. Physiol. - 2014; 143: 679-92.
  7. FollonierCastella L., Gabbiani G., McCulloch C. et al. Regulation of myofibroblast activities: calcium pulls some strings behind the scene // Exp. Cell Res. - 2010; 316: 2390-401.
  8. Kawamura A., Miura S., Matsuo Y. et al. Azelnidipine, Not Amlodipine, Induces Secretion of Vascular Endothelial Growth Factor From Smooth Muscle Cells and Promotes Endothelial Tube Formation // Cardiol. Res. - 2014; 5 (5): 145-50. ВРАЧ 4'2016
  9. Li Y., Lorca R., Ma X. et al. BK Channels Regulate Myometrial Contraction by Modulating Nuclear Translocation of NF-kB // Endocrinology. - 2014; 155 (8): 3112-22.
  10. Ishii N., Matsumura T., Shimodа S. et al. Anti-atherosclerotic potential of dihydropyridine calcium channel blockers // J. Atheroscl. Thromb. - 2012; 19 (8): 693-704.
  11. Mukherjee S., Kolb M., Duan F. et al. Transforming growth factor-ß evokes Ca2+waves and enhances gene expression in human pulmonary fibroblasts // Am. J. Respir. Cell Mol. Biol. - 2012; 46: 757-64.
  12. Costabel U. Emerging potential treatments: new hope for idiopathic pulmonary fibrosis patients? // Eur. Respir. Rev. - 2011; 20: 201-7.
  13. Kaddour-Djebbar I., Choudhary V., Lakshmikanthan V. et al. Diltiazem enhances the apoptotic effects of proteasome inhibitors to induce prostate cancer cell death // J. Pharmacol. Exp. Ther. - 2012; 341 (3): 646-55.
  14. Meggyeshazi N., Andocs G., Balogh. L. et al. DNA fragmentation and caspase-independent programmed cell death by modulated electrohyperthermia // Strahlentherapie und Onkologie. - 2014; 190 (9): 815-22.
  15. Wang R., Mao Y., Zhang Z. et al. Role of verapamil in preventing and treating hypertrophic scars and keloids // Int. Wound J. - 2015; doi: 10.1111/ iwj.12455.
  16. Li Y., Ma X., Yu P. et al. Intra-articular adhesion reduction after knee surgery in rabbits by calcium channel blockers // Med SciMonit. - 2014; 20: 2466-71.
  17. Wang Z., Wang Y., Xie P. et al. Calcium channel blockers in reduction of epidural fibrosis and dural adhesions in laminectomy rats // Eur. J. Orthop. Surg. Traumatol. - 2014; 24 (1): 293-8.
  18. Скальский С.В. Влияние верапамила на продукцию противовоспалительных цитокинов перитонеальными мононуклеарами // Вестник РАМН. -2010; 3: 33-5.
  19. Скальский С.В. Влияние верапамила на процесс перитонеального спайкообразования в эксперименте // Медицина в Кузбассе. - 2012; 11 (3): 15-8.

补充文件

附件文件
动作
1. JATS XML
##common.cookie##